Chronic granulomatous disease in two children with recurrent infections: family studies using dihydrorhodamine-based flow cytometry.

We employed a recently published technique, flow cytometry using the cell permeant dye dihydrorhodamine, to analyze families of two patients with X-linked chronic granulomatous disease. The results illustrate the utility of this method in the diagnosis of this serious immunodeficiency disease and also in the identification of carriers.