| Literature DB >> 9061203 |
F A Kerdesky1, C D Brooks, K I Hulkower, J B Bouska, R L Bell.
Abstract
Representative examples of NSAID cyclooxygenase inhibitors such as naproxen, ibufenac, ibuprofen, and butibufen have been transformed into 5-lipoxygenase inhibitors by replacement of the carboxylic acid moiety with a 4-hydroxythiazole group.Entities:
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Year: 1997 PMID： 9061203 DOI： 10.1016/s0968-0896(96)00255-6
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641