| Literature DB >> 9060966 |
G S Roth1, M A Kowatch, J Hengemihle, D K Ingram, E L Spangler, L K Johnson, M A Lane.
Abstract
Cutaneous wounds close more slowly in rats and monkeys as age increases. Caloric restriction of 40% in rats and 30% in monkeys did not significantly affect healing rates, although it did exert a trend toward faster closure. Similarly, voluntary exercise did not significantly alter healing rates in rats. Thus, impaired wound healing appears to be a generalized physiological manifestation of aging, but its possible amelioration by "anti-aging" interventions remains to be established.Entities:
Mesh：
Year: 1997 PMID： 9060966 DOI： 10.1093/gerona/52a.2.b98
Source DB: PubMed Journal: J Gerontol A Biol Sci Med Sci ISSN： 1079-5006 Impact factor: 6.053