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10 in total

1. Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes.

Authors: Angelica R Harper; Anh T Le; Timothy Mather; Anthony Burgett; William Berry; Jody A Summers
Journal: Bioorg Med Chem Date: 2018-10-24 Impact factor: 3.641

2. Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro.

Authors: Xian-Qing Zhang; Xiao-Feng Huang; Xing-Bin Hu; Yong-Hua Zhan; Qun-Xing An; Shi-Ming Yang; Ai-Jun Xia; Jing Yi; Rui Chen; Shi-Jie Mu; Dao-Cheng Wu
Journal: Asian J Androl Date: 2010-07-26 Impact factor: 3.285

Review 3. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application.

Authors: Vindhya Koppaka; David C Thompson; Ying Chen; Manuel Ellermann; Kyriacos C Nicolaou; Risto O Juvonen; Dennis Petersen; Richard A Deitrich; Thomas D Hurley; Vasilis Vasiliou
Journal: Pharmacol Rev Date: 2012-04-27 Impact factor: 25.468

4. A point mutation produced a class 3 aldehyde dehydrogenase with increased protective ability against the killing effect of cyclophosphamide.

Authors: Kwok Ki Ho; Abhijit Mukhopadhyay; Yi Feng Li; Soma Mukhopadhyay; Henry Weiner
Journal: Biochem Pharmacol Date: 2008-07-04 Impact factor: 5.858

5. Aldehyde dehydrogenase is used by cancer cells for energy metabolism.

Authors: Joon Hee Kang; Seon-Hyeong Lee; Dongwan Hong; Jae-Seon Lee; Hee-Sung Ahn; Ju-Hyun Ahn; Tae Wha Seong; Chang-Hun Lee; Hyonchol Jang; Kyeong Man Hong; Cheolju Lee; Jae-Ho Lee; Soo-Youl Kim
Journal: Exp Mol Med Date: 2016-11-25 Impact factor: 8.718

Inhibition of human class 3 aldehyde dehydrogenase, and sensitization of tumor cells that express significant amounts of this enzyme to oxazaphosphorines, by the naturally occurring compound gossypol.

1. Design, synthesis, and ex vivo evaluation of a selective inhibitor for retinaldehyde dehydrogenase enzymes.

2. Apogossypolone, a novel inhibitor of antiapoptotic Bcl-2 family proteins, induces autophagy of PC-3 and LNCaP prostate cancer cells in vitro.

Review 3. Aldehyde dehydrogenase inhibitors: a comprehensive review of the pharmacology, mechanism of action, substrate specificity, and clinical application.

4. A point mutation produced a class 3 aldehyde dehydrogenase with increased protective ability against the killing effect of cyclophosphamide.

5. Aldehyde dehydrogenase is used by cancer cells for energy metabolism.

6. Aldehyde dehydrogenase inhibition combined with phenformin treatment reversed NSCLC through ATP depletion.

7. Gastric cancer depends on aldehyde dehydrogenase 3A1 for fatty acid oxidation.

8. Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start?

9. PDE5 inhibition eliminates cancer stem cells via induction of PKA signaling.

10. Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres.