Auditory deprivation modifies sleep in the guinea-pig.

After destruction of both cochleae, a significant enhancement of both paradoxical sleep and slow wave sleep together with decreased wakefulness, were observed for up to 45 days. The sleep augmentation consisted of an increment in the number of episodes of both slow wave and paradoxical sleep rather than in the duration of single episodes. The partial isolation provoked by deafness is postulated as explanation. We suggest that the suppression of one input to a complex set of networks related to the sleep-waking cycle, introduce an imbalance that leads to sleep enhancement.