Literature DB >> 9056022

Novel extended-spectrum TEM-type beta-lactamase from an Escherichia coli isolate resistant to ceftazidime and susceptible to cephalothin.

C Chanal-Claris1, D Sirot, L Bret, P Chatron, R Labia, J Sirot.   

Abstract

A novel extended-spectrum TEM-type beta-lactamase was detected in an Escherichia coli isolate which was resistant to ceftazidime and susceptible to cephalothin. The corresponding bla gene was sequenced. The deduced amino acid sequence showed the following three amino acid replacements with respect to the TEM-2 sequence: Glu-->Lys-104, Arg-->Ser-164, and Glu-->Lys-240. Since it confers a ceftazidimase-type resistance phenotype, we propose for this novel enzyme the designation CAZ-9, corresponding to TEM-46 in the sequential numbering scheme of TEM beta-lactamases.

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Year:  1997        PMID： 9056022      PMCID： PMC163780     

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  15 in total

1.  A standard numbering scheme for the class A beta-lactamases.

Authors:  R P Ambler; A F Coulson; J M Frère; J M Ghuysen; B Joris; M Forsman; R C Levesque; G Tiraby; S G Waley
Journal:  Biochem J       Date:  1991-05-15       Impact factor: 3.857

2.  Substrate specificities in class A beta-lactamases: preference for penams vs. cephems. The role of residue 237.

Authors:  W J Healey; M R Labgold; J H Richards
Journal:  Proteins       Date:  1989

3.  Structural basis of extended spectrum TEM beta-lactamases. Crystallographic, kinetic, and mass spectrometric investigations of enzyme mutants.

Authors:  L Maveyraud; I Saves; O Burlet-Schiltz; P Swarén; J M Masson; M Delaire; L Mourey; J C Promé; J P Samama
Journal:  J Biol Chem       Date:  1996-05-03       Impact factor: 5.157

4.  Interactions of new plasmid-mediated beta-lactamases with third-generation cephalosporins.

Authors:  R Labia; A Morand; K Tiwari; J Sirot; D Sirot; A Petit
Journal:  Rev Infect Dis       Date:  1988 Jul-Aug

5.  A novel chromosomal TEM derivative and alterations in outer membrane proteins together mediate selective ceftazidime resistance in Escherichia coli.

Authors:  D A Weber; C C Sanders; J S Bakken; J P Quinn
Journal:  J Infect Dis       Date:  1990-08       Impact factor: 5.226

6.  Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.

Authors:  V Jarlier; M H Nicolas; G Fournier; A Philippon
Journal:  Rev Infect Dis       Date:  1988 Jul-Aug

7.  Nucleotide sequence of the ampicillin resistance gene of Escherichia coli plasmid pBR322.

Authors:  J G Sutcliffe
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

8.  Computerized microacidimetric determination of beta lactamase Michaelis-Menten constants.

Authors:  R Labia; J Andrillon; F Le Goffic
Journal:  FEBS Lett       Date:  1973-06-15       Impact factor: 4.124

9.  Multiplicity of TEM-derived beta-lactamases from Klebsiella pneumoniae strains isolated at the same hospital and relationships between the responsible plasmids.

Authors:  C M Chanal; D L Sirot; A Petit; R Labia; A Morand; J L Sirot; R A Cluzel
Journal:  Antimicrob Agents Chemother       Date:  1989-11       Impact factor: 5.191

10.  Substitution of lysine at position 104 or 240 of TEM-1pTZ18R beta-lactamase enhances the effect of serine-164 substitution on hydrolysis or affinity for cephalosporins and the monobactam aztreonam.

Authors:  J A Sowek; S B Singer; S Ohringer; M F Malley; T J Dougherty; J Z Gougoutas; K Bush
Journal:  Biochemistry       Date:  1991-04-02       Impact factor: 3.162
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  4 in total

1.  Quantifying nonspecific TEM beta-lactamase (blaTEM) genes in a wastewater stream.

Authors:  Karen L Lachmayr; Lee J Kerkhof; A Gregory Dirienzo; Colleen M Cavanaugh; Timothy E Ford
Journal:  Appl Environ Microbiol       Date:  2008-11-07       Impact factor: 4.792

Review 2.  Catalytic properties of class A beta-lactamases: efficiency and diversity.

Authors:  A Matagne; J Lamotte-Brasseur; J M Frère
Journal:  Biochem J       Date:  1998-03-01       Impact factor: 3.857

3.  Evolution of TEM-type extended-spectrum beta-lactamases in clinical Enterobacteriaceae strains in Poland.

Authors:  Anna Baraniak; Janusz Fiett; Agnieszka Mrówka; Jarosław Walory; Waleria Hryniewicz; Marek Gniadkowski
Journal:  Antimicrob Agents Chemother       Date:  2005-05       Impact factor: 5.191

Review 4.  Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases.

Authors:  Timothy Palzkill
Journal:  Front Mol Biosci       Date:  2018-02-23
  4 in total

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