| Literature DB >> 9055809 |
J Dakour1, H Li, D W Morrish.
Abstract
The cDNA for a novel gene, PL48, isolated by subtractive hybridization between undifferentiated human term cytotrophoblast and differentiating cytotrophoblast, has been cloned and sequenced. PL48 contains an open reading frame coding for a 537-amino acid protein, has multiple potential PKC, casein kinase II, and cAMP/cGMP-dependent kinase phosphorylation sites, and N-linked glycosylation sites. It is not present in a wide variety of proliferating cancer cells, but PL48 mRNA shows marked expression during cytotrophoblast and granulocyte lineage-specific HL-60 promyelocytic cell differentiation induced by DMSO.Entities:
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Year: 1997 PMID： 9055809 DOI： 10.1016/s0378-1119(96)00587-2
Source DB: PubMed Journal: Gene ISSN： 0378-1119 Impact factor: 3.688