Malignant fibrous histiocytomas of the larynx--report of two cases.

Malignant fibrous histiocytoma of the larynx is a rare entity. It is even more infrequent for the tumour to arise from a specific location on the larynx namely the vocal cords. We report two cases of vocal cord malignant fibrous histiocytoma, one in a 27-year old man who underwent frontal partial laryngectomy, and the other in a 57-year old man who was managed with total laryngectomy. Both patients remain disease-free after 5 years of follow-up. We present a discussion of the available literature on this subject. As these tumours occur very infrequently, no one centre is able to acquire the prerequisite amount of experience to be able to lay down firm scientifically based guidelines on the management of these tumours. It is thus inevitable that whatever evidence we have is purely anecdotal in nature.