Literature DB >> 9054476

Use of stable isotopically labeled tracers for studies of metabolic kinetics: an overview.

B W Patterson1.   

Abstract

Stable isotopically labeled tracers offer a reliable and safe alternative to the use of radioactive tracers for studies of metabolic kinetics. This overview examines some of the principles and technical issues regarding mass spectrometry instrumentation, and reviews some of the approaches used in the application of stable isotopically labeled tracers to studies of protein, lipid, and carbohydrate metabolic kinetics.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9054476     DOI： 10.1016/s0026-0495(97)90260-2

Source DB:  PubMed          Journal:  Metabolism        ISSN： 0026-0495            Impact factor:   8.694


  13 in total

1.  Measurement of human surfactant protein-B turnover in vivo from tracheal aspirates using targeted proteomics.

Authors:  Daniela M Tomazela; Bruce W Patterson; Elizabeth Hanson; Kimberly L Spence; Tiffany B Kanion; David H Salinger; Paolo Vicini; Hugh Barret; Hillary B Heins; F Sessions Cole; Aaron Hamvas; Michael J MacCoss
Journal:  Anal Chem       Date:  2010-03-15       Impact factor: 6.986

2.  Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo.

Authors:  Randall J Bateman; Ling Y Munsell; John C Morris; Robert Swarm; Kevin E Yarasheski; David M Holtzman
Journal:  Nat Med       Date:  2006-06-25       Impact factor: 53.440

3.  Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease.

Authors:  Kerry L Donnelly; Coleman I Smith; Sarah J Schwarzenberg; Jose Jessurun; Mark D Boldt; Elizabeth J Parks
Journal:  J Clin Invest       Date:  2005-05       Impact factor: 14.808

4.  Increased de novo lipogenesis is a distinct characteristic of individuals with nonalcoholic fatty liver disease.

Authors:  Jennifer E Lambert; Maria A Ramos-Roman; Jeffrey D Browning; Elizabeth J Parks
Journal:  Gastroenterology       Date:  2013-12-04       Impact factor: 22.682

5.  Stable isotope labeling tandem mass spectrometry (SILT) to quantify protein production and clearance rates.

Authors:  Randall J Bateman; Ling Y Munsell; Xianghong Chen; David M Holtzman; Kevin E Yarasheski
Journal:  J Am Soc Mass Spectrom       Date:  2007-02-22       Impact factor: 3.109

6.  Analysis of a compartmental model of amyloid beta production, irreversible loss and exchange in humans.

Authors:  Donald L Elbert; Bruce W Patterson; Randall J Bateman
Journal:  Math Biosci       Date:  2014-12-09       Impact factor: 2.144

7.  Artificial gravity maintains skeletal muscle protein synthesis during 21 days of simulated microgravity.

Authors:  T B Symons; M Sheffield-Moore; D L Chinkes; A A Ferrando; D Paddon-Jones
Journal:  J Appl Physiol (1985)       Date:  2009-04-23

8.  Amino acid supplementation increases lean body mass, basal muscle protein synthesis, and insulin-like growth factor-I expression in older women.

Authors:  Edgar L Dillon; Melinda Sheffield-Moore; Douglas Paddon-Jones; Charles Gilkison; Arthur P Sanford; Shanon L Casperson; Jie Jiang; David L Chinkes; Randall J Urban
Journal:  J Clin Endocrinol Metab       Date:  2009-02-10       Impact factor: 5.958

9.  Dietary fat and carbohydrates differentially alter insulin sensitivity during caloric restriction.

Authors:  Erik Kirk; Dominic N Reeds; Brian N Finck; S Mitra Mayurranjan; Mitra S Mayurranjan; Bruce W Patterson; Samuel Klein
Journal:  Gastroenterology       Date:  2009-01-25       Impact factor: 22.682

10.  Lipoprotein kinetics in the metabolic syndrome: pathophysiological and therapeutic lessons from stable isotope studies.

Authors:  Dick C Chan; P Hugh R Barrett; Gerald F Watts
Journal:  Clin Biochem Rev       Date:  2004-02
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.