Literature DB >> 9052624

Hypotony maculopathy after filtering surgery with mitomycin C. Incidence and treatment.

I J Suñer1, D S Greenfield, M P Miller, M T Nicolela, P F Palmberg.   

Abstract

PURPOSE: Hypotony maculopathy after glaucoma filtering surgery with adjunctive mitomycin C has been reported to occur in 3% to 14% of cases. The authors evaluated its incidence when using a corneal safety-valve incisior intended to reduce its occurrence. The authors also evaluated a technique for reversing hypotony maculopathy by reoperation using two sets of stitches in the scleral flap, with one set tied tightly to temporarily raise the intraocular pressure, stretch the sclera, and flatten chorioretinal folds.
METHODS: The authors reviewed the results of 699 procedures performed between April 1991 and October 1994. All were performed or supervised by one surgeon (PFP).
RESULTS: Hypotony maculopathy developed in 9 (1.3%) of 699 eyes. There was a statistically significant higher incidence in primary filters (4%) as compared to secondary filters or combined procedures. After revision, eight (89%) of nine recovered visual acuity of greater than or equal to 20/30 and the mean intraocular pressure was 14.5 +/- 4 mmHg at a mean follow-up of 15 months.
CONCLUSION: The incidence of hypotony maculopathy after glaucoma filtering surgery with mitomycin C using a corneal safety-valve incision is less than that reported in the literature without this incision. There is an increased risk in myopes, young patients, and primary filters. Early intervention with the described scleral flap revision technique usually allows restoration of prefiltration visual acuity without compromise of bleb function.

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Year:  1997        PMID: 9052624     DOI: 10.1016/s0161-6420(97)30332-7

Source DB:  PubMed          Journal:  Ophthalmology        ISSN: 0161-6420            Impact factor:   12.079


  30 in total

1.  The safety and efficacy of combined phacoemulsification and trabeculectomy with releasable sutures.

Authors:  W J Stark; R K Goyal; O Awad; E Vito; A C Kouzis
Journal:  Br J Ophthalmol       Date:  2006-02       Impact factor: 4.638

2.  Changes in axial length following trabeculectomy and glaucoma drainage device surgery.

Authors:  B A Francis; M Wang; H Lei; L T Du; D S Minckler; R L Green; C Roland
Journal:  Br J Ophthalmol       Date:  2005-01       Impact factor: 4.638

3.  Changes in choroidal thickness, axial length, and ocular perfusion pressure accompanying successful glaucoma filtration surgery.

Authors:  N Kara; O Baz; C Altan; B Satana; T Kurt; A Demirok
Journal:  Eye (Lond)       Date:  2013-06-07       Impact factor: 3.775

4.  Endothelial cell changes after photorefractive keratectomy with graded usage of mitomycin C.

Authors:  Hamid Gharaee; Siamak Zarei-Ghanavati; Reza Alizadeh; Mojtaba Abrishami
Journal:  Int Ophthalmol       Date:  2017-06-13       Impact factor: 2.031

5.  Dented corneas related to cardiovascular surgery under general anesthesia.

Authors:  Tomoko Hasegawa; Yoshie Matsui; Masafumi Morita
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-03-30       Impact factor: 3.117

6.  Effects of daunorubicin, mitomycin C, azathioprine and cyclosporin A on human retinal pigmented epithelial, corneal endothelial and conjunctival cell lines.

Authors:  Justus G Garweg; Maria Wegmann-Burns; David Goldblum
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-08-10       Impact factor: 3.117

Review 7.  [Glaucoma treatment in high myopia].

Authors:  B Voykov; J M Rohrbach
Journal:  Ophthalmologe       Date:  2019-05       Impact factor: 1.059

8.  Aberrant wound-healing response in mitomycin C-treated leaking blebs: a histopathologic study.

Authors:  Victor M Elner; Paula Anne Newman-Casey; A Jayaprakash Patil; Andrew Flint; Jyotirmay Biswas; Sayoko E Moroi; Vaijayanthi Pushparaj; Deepak P Edward
Journal:  Arch Ophthalmol       Date:  2009-08

9.  Effect of axial length reduction after trabeculectomy on the development of hypotony maculopathy.

Authors:  Yoshiko Matsumoto; Masashi Fujihara; Akiyasu Kanamori; Yuko Yamada; Makoto Nakamura
Journal:  Jpn J Ophthalmol       Date:  2014-03-04       Impact factor: 2.447

10.  Flap suture--a simple technique for the revision of hypotony maculopathy following trabeculectomy with mitomycin C.

Authors:  Judith Eha; Esther M Hoffmann; Jochen Wahl; Norbert Pfeiffer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2008-04-04       Impact factor: 3.117

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