BACKGROUND: This study was designed to assess the impact of oxygen transport variables on outcome in 115 patients undergoing elective surgery for oesophageal carcinoma. METHODS: Haemodynamic parameters were determined using a Swan-Ganz catheter in all patients on the day before operation, 6 h after operation, and daily for the first 4 days after operation. RESULTS: Oxygen delivery and consumption at 6 h were significantly higher in survivors than in non-survivors. However, oxygen delivery and consumption in both groups did not differ significantly after postoperative day 1. Of 17 patients with oxygen delivery levels lower than 445 ml min-1 m-2 at 6 h, eight died in hospital. Oxygen delivery in patients who developed either an anastomotic leak or severe pneumonia was significantly lower 6 h after surgery. Lower levels of oxygen delivery preceded postoperative complications. CONCLUSION: Oxygen delivery 6 h after oesophagectomy correlates with postoperative complications and may be a determinant of hospital mortality.
BACKGROUND: This study was designed to assess the impact of oxygen transport variables on outcome in 115 patients undergoing elective surgery for oesophageal carcinoma. METHODS: Haemodynamic parameters were determined using a Swan-Ganz catheter in all patients on the day before operation, 6 h after operation, and daily for the first 4 days after operation. RESULTS:Oxygen delivery and consumption at 6 h were significantly higher in survivors than in non-survivors. However, oxygen delivery and consumption in both groups did not differ significantly after postoperative day 1. Of 17 patients with oxygen delivery levels lower than 445 ml min-1 m-2 at 6 h, eight died in hospital. Oxygen delivery in patients who developed either an anastomotic leak or severe pneumonia was significantly lower 6 h after surgery. Lower levels of oxygen delivery preceded postoperative complications. CONCLUSION:Oxygen delivery 6 h after oesophagectomy correlates with postoperative complications and may be a determinant of hospital mortality.
Authors: Darmarajah Veeramootoo; Rajeev Parameswaran; Rakesh Krishnadas; Peter Froeschle; Martin Cooper; Richard G Berrisford; Shahjehan A Wajed Journal: Surg Endosc Date: 2008-12-06 Impact factor: 4.584
Authors: Rupert Pearse; Deborah Dawson; Jayne Fawcett; Andrew Rhodes; R Michael Grounds; E David Bennett Journal: Crit Care Date: 2005-11-08 Impact factor: 9.097
Authors: Rupert Pearse; Deborah Dawson; Jayne Fawcett; Andrew Rhodes; R Michael Grounds; E David Bennett Journal: Crit Care Date: 2005-11-08 Impact factor: 9.097
Authors: Jonathan Sivakumar; Harry Sivakumar; Matthew Read; Rhona C F Sinclair; Chistopher P Snowden; Michael W Hii Journal: Ann Surg Oncol Date: 2020-06-02 Impact factor: 5.344