Literature DB >> 9051915

Illudinic acid, a novel illudane sesquiterpene antibiotic.

C Dufresne1, K Young, F Pelaez, A Gonzalez del Val, D Valentino, A Graham, G Platas, A Bernard, D Zink.   

Abstract

A novel illudane sesquiterpene antibiotic (1) with activity against methicillin-resistant Staphylococcus aureus (MRSA), has been isolated. Its MIC against MRSA was found to be 16 micrograms/mL. It also shows L-1210 cytotoxicity with an IC50 of 10-15 micrograms/mL.

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Year:  1997        PMID: 9051915     DOI: 10.1021/np960596x

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  1 in total

1.  Synthesis of 2,2-Disubstituted Pentalenes and Indenes by a Useful Modification to Nakamura's DMCP [3+2]-Cycloaddition Protocol.

Authors:  Todd A Wenderski; Vincent Denatale; Thomas R R Pettus
Journal:  Synlett       Date:  2009-10-01       Impact factor: 2.454

  1 in total

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