Literature DB >> 9051909

New sesquiterpene hydroquinones from a Taiwanese marine sponge Polyfibrospongia australis.

Y C Shen1, P W Hsieh.   

Abstract

Two new sesquiterpene hydroquinones, polyfibrospongols A (1) and B (2), were isolated from the Taiwanese marine sponge Polyfibrospongia australis Lendenfeld (Spongiidae) in addition to the known metabolites, dictyoceratin A (3), ilimaquinone (4), and 5-epi-ilimaquinone (9). The structures of these compounds have been determined mainly on the basis of spectral and chemical methods. Biological testing revealed that compounds 1 and 2 exhibited significant cytotoxicity against human KB-16, A-549, and murine P-388 tumor cell lines.

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Year:  1997        PMID: 9051909     DOI: 10.1021/np9605302

Source DB:  PubMed          Journal:  J Nat Prod        ISSN: 0163-3864            Impact factor:   4.050


  7 in total

Review 1.  Reactivity and biological activity of the marine sesquiterpene hydroquinone avarol and related compounds from sponges of the order Dictyoceratida.

Authors:  Dusan Sladić; Miroslav J Gasić
Journal:  Molecules       Date:  2006-01-31       Impact factor: 4.411

2.  Inducers of hypoxic response: marine sesquiterpene quinones activate HIF-1.

Authors:  Lin Du; Yu-Dong Zhou; Dale G Nagle
Journal:  J Nat Prod       Date:  2013-06-03       Impact factor: 4.050

Review 3.  Cytotoxic terpene quinones from marine sponges.

Authors:  Marina Gordaliza
Journal:  Mar Drugs       Date:  2010-11-24       Impact factor: 5.118

4.  Xishaeleganins A-D, Sesquiterpenoid Hydroquinones from Xisha Marine Sponge Dactylospongia elegans.

Authors:  Bao Chen; Qingmin Zhao; Yu-Cheng Gu; Lefu Lan; Chang-Yun Wang; Yue-Wei Guo
Journal:  Mar Drugs       Date:  2022-02-01       Impact factor: 5.118

5.  Pro-Apoptotic Activity of the Marine Sponge Dactylospongia elegans Metabolites Pelorol and 5-epi-Ilimaquinone on Human 501Mel Melanoma Cells.

Authors:  Sara Carpi; Egeria Scoditti; Beatrice Polini; Simone Brogi; Vincenzo Calderone; Peter Proksch; Sherif S Ebada; Paola Nieri
Journal:  Mar Drugs       Date:  2022-06-28       Impact factor: 6.085

6.  Synthesis of two new hemisynthetic diterpenylhydroquinones from natural ent-labdanes.

Authors:  Luis Espinoza Catalán; Karen Catalán Marín; Alejandro Madrid Villegas; Héctor Carrasco Altamirano; Joan Villena García; Mauricio Cuellar Fritis
Journal:  Molecules       Date:  2009-06-17       Impact factor: 4.411

7.  A new sesquiterpenoid hydroquinone from the marine sponge Dysidea arenaria.

Authors:  Yan Qiu; Xiu Min Wang
Journal:  Molecules       Date:  2008-06-06       Impact factor: 4.411

  7 in total

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