Literature DB >> 9049574

Gradual withdrawal from benzodiazepines in residents of homes for the elderly: experience and suggestions for future research.

H Habraken1, K Soenen, L Blondeel, J Van Elsen, J Bourda, E Coppens, M Willeput.   

Abstract

OBJECTIVE: A randomised, controlled clinical trial was performed to study the long-term effect of gradual withdrawal from benzodiazepines on the daily functioning of residents of homes for the elderly. The planned sample size was not achieved due to recruitment and follow-up problems.
RESULTS: The results in this small sample nevertheless suggest that gradual withdrawal from benzodiazepines is possible in residents of homes for the elderly, and that it can have a positive effect on their daily functioning. No major withdrawal symptoms were observed, although there was a decrease in sleep quality during withdrawal.
CONCLUSION: The findings are promising for further research, but researchers should anticipate the problems inherent in executing a trial with institutionalised elderly subjects.

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Year:  1997        PMID： 9049574     DOI： 10.1007/s002280050213

Source DB:  PubMed          Journal:  Eur J Clin Pharmacol        ISSN： 0031-6970            Impact factor:   2.953


  12 in total

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Journal:  Tijdschr Gerontol Geriatr       Date:  1986-02

8.  The Benzodiazepine Withdrawal Symptom Questionnaire.

Authors:  P Tyrer; S Murphy; P Riley
Journal:  J Affect Disord       Date:  1990-05       Impact factor: 4.839

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Authors:  M J Giblin; A D Clift
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Authors:  A Gilbert; N Owen; J M Innes; L Sansom
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Review 5.  Medication withdrawal trials in people aged 65 years and older: a systematic review.

Authors:  Shoba Iyer; Vasi Naganathan; Andrew J McLachlan; David G Le Couteur
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Review 6.  The feasibility and effect of deprescribing in older adults on mortality and health: a systematic review and meta-analysis.

Authors:  Amy T Page; Rhonda M Clifford; Kathleen Potter; Darren Schwartz; Christopher D Etherton-Beer
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Review 7.  A systematic mapping review of randomized controlled trials (RCTs) in care homes.

Authors:  Adam L Gordon; Phillipa A Logan; Rob G Jones; Calum Forrester-Paton; Jonathan P Mamo; John R F Gladman
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8.  Handgrip strength and balance in older adults following withdrawal from long-term use of temazepam, zopiclone or zolpidem as hypnotics.

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