Literature DB >> 9042136

Outcome of acetaminophen overdose in pediatric patients and factors contributing to hepatotoxicity.

T Rivera-Penera1, R Gugig, J Davis, S McDiarmid, J Vargas, P Rosenthal, W Berquist, M B Heyman, M E Ament.   

Abstract

Seventy-three medical records of pediatric patients admitted for acetaminophen overdose were reviewed. Twenty-eight patients (39%) had severe liver toxic effects, and six of them underwent liver transplantation. Multiple miscalculated overdoses given by parents, with delay in therapy, are risk factors and the major cause of overdose in children 10 years of age or younger.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9042136     DOI: 10.1016/s0022-3476(97)70359-7

Source DB:  PubMed          Journal:  J Pediatr        ISSN: 0022-3476            Impact factor:   4.406


  38 in total

Review 1.  Risks and benefits of nonsteroidal anti-inflammatory drugs in children: a comparison with paracetamol.

Authors:  C Litalien; E Jacqz-Aigrain
Journal:  Paediatr Drugs       Date:  2001       Impact factor: 3.022

2.  Reye's syndrome revisited. Outdated concept of Reye's syndrome was used.

Authors:  M Casteels-Van Daele; C Wouters; C Van Geet; M C McGovern; J F T Glasgow; M C Stewart
Journal:  BMJ       Date:  2002-03-02

3.  A model for size and age changes in the pharmacokinetics of paracetamol in neonates, infants and children.

Authors:  B J Anderson; G A Woollard; N H Holford
Journal:  Br J Clin Pharmacol       Date:  2000-08       Impact factor: 4.335

4.  Time to counter 'fever phobia'!

Authors:  Wouter Havinga
Journal:  Br J Gen Pract       Date:  2003-03       Impact factor: 5.386

5.  An oral history of general practice. 10: Diagnostics and therapeutics.

Authors:  Graham Smith; Malcolm Nicolson
Journal:  Br J Gen Pract       Date:  2003-03       Impact factor: 5.386

6.  GP pay--naming the elephants.

Authors:  Paul Hodgkin
Journal:  Br J Gen Pract       Date:  2003-03       Impact factor: 5.386

7.  [Opioids or paracetamol for postoperative analgesia in newborns and small children?].

Authors:  Dorothee H Bremerich; Paul Kessler; G Neidhart
Journal:  Anaesthesist       Date:  2002-07       Impact factor: 1.041

8.  Fever: to treat or not to treat?

Authors:  Miguel Glatstein; Dennis Scolnik
Journal:  World J Pediatr       Date:  2008-12-23       Impact factor: 2.764

Review 9.  [Therapy of perioperative pain in pediatric urology].

Authors:  J-H Hilpert; P Reinhold
Journal:  Urologe A       Date:  2009-10       Impact factor: 0.639

10.  Pain relief in children. Doing the simple things better.

Authors:  M Zacharias; D Watts
Journal:  BMJ       Date:  1998-05-23
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.