Literature DB >> 9041672

A recombinant canarypox virus protects rabbits against a lethal rabbit hemorrhagic disease virus (RHDV) challenge.

L Fischer1, F X Le Gros, P W Mason, E Paoletti.   

Abstract

An ALVAC (canarypox)-based recombinant virus ALVAC-RHDV (vCP309) expressing a native rabbit hemorrhagic disease virus (RHDV) capsid protein was derived and assessed for its protective efficacy in rabbits. Protection against a lethal RHDV challenge was demonstrated in rabbits inoculated twice with either high (10(7) p.f.u.) or low (10(5) p.f.u.) doses of vCP309. However, animals in the high dose group developed significantly higher antibody response. These results have implications that are relevant to the development of a safe rabbit hemorrhagic disease (RHD) vaccine and further illustrate the utility of the ALVAC vector system to elicit protective immune responses in nonavian species.

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Year:  1997        PMID： 9041672     DOI： 10.1016/s0264-410x(96)00102-8

Source DB:  PubMed          Journal:  Vaccine        ISSN： 0264-410X            Impact factor:   3.641


  15 in total

1.  Strict Assembly Restriction of Peptides from Rabbit Hemorrhagic Disease Virus Presented by Rabbit Major Histocompatibility Complex Class I Molecule RLA-A1.

Authors:  Qingxu Zhang; Kefang Liu; Can Yue; Di Zhang; Dan Lu; Wenling Xiao; Peipei Liu; Yingze Zhao; Guolan Gao; Chunming Ding; Jianxin Lyu; William J Liu
Journal:  J Virol       Date:  2020-08-17       Impact factor: 5.103

2.  Horizontal transmissible protection against myxomatosis and rabbit hemorrhagic disease by using a recombinant myxoma virus.

Authors:  J Bárcena; M Morales; B Vázquez; J A Boga; F Parra; J Lucientes; A Pagès-Manté; J M Sánchez-Vizcaíno; R Blasco; J M Torres
Journal:  J Virol       Date:  2000-02       Impact factor: 5.103

3.  Transient, nonlethal expression of genes in vertebrate cells by recombinant entomopoxviruses.

Authors:  Y Li; R L Hall; R W Moyer
Journal:  J Virol       Date:  1997-12       Impact factor: 5.103

4.  Canarypox virus-induced maturation of dendritic cells is mediated by apoptotic cell death and tumor necrosis factor alpha secretion.

Authors:  R Ignatius; M Marovich; E Mehlhop; L Villamide; K Mahnke; W I Cox; F Isdell; S S Frankel; J R Mascola; R M Steinman; M Pope
Journal:  J Virol       Date:  2000-12       Impact factor: 5.103

Review 5.  Rabbit haemorrhagic disease (RHD) and rabbit haemorrhagic disease virus (RHDV): a review.

Authors:  Joana Abrantes; Wessel van der Loo; Jacques Le Pendu; Pedro J Esteves
Journal:  Vet Res       Date:  2012-02-10       Impact factor: 3.683

Review 6.  The evolution of poxvirus vaccines.

Authors:  Lucas Sánchez-Sampedro; Beatriz Perdiguero; Ernesto Mejías-Pérez; Juan García-Arriaza; Mauro Di Pilato; Mariano Esteban
Journal:  Viruses       Date:  2015-04-07       Impact factor: 5.048

7.  The non-pathogenic Australian rabbit calicivirus RCV-A1 provides temporal and partial cross protection to lethal Rabbit Haemorrhagic Disease Virus infection which is not dependent on antibody titres.

Authors:  Tanja Strive; Peter Elsworth; June Liu; John D Wright; John Kovaliski; Lorenzo Capucci
Journal:  Vet Res       Date:  2013-07-08       Impact factor: 3.683

8.  Codon optimization of the rabbit hemorrhagic disease virus (RHDV) capsid gene leads to increased gene expression in Spodoptera frugiperda 9 (Sf9) cells.

Authors:  Jingpeng Gao; Chunchun Meng; Zongyan Chen; Chuanfeng Li; Guangqing Liu
Journal:  J Vet Sci       Date:  2013-06-30       Impact factor: 1.672

Review 9.  Viral vectors for veterinary vaccines.

Authors:  M Sheppard
Journal:  Adv Vet Med       Date:  1999

10.  Conformational and thermal stability improvements for the large-scale production of yeast-derived rabbit hemorrhagic disease virus-like particles as multipurpose vaccine.

Authors:  Erlinda Fernández; Jorge R Toledo; Lídice Méndez; Nemecio González; Francisco Parra; José M Martín-Alonso; Miladys Limonta; Kosara Sánchez; Ania Cabrales; Mario P Estrada; Alina Rodríguez-Mallón; Omar Farnós
Journal:  PLoS One       Date:  2013-02-27       Impact factor: 3.240
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