Literature DB >> 9037628

Immunodiagnosis of prion disease.

R J Kascsak1, R Fersko, D Pulgiano, R Rubenstein, R I Carp.   

Abstract

The immunodiagnosis of prion diseases is of critical importance due to the transmissibility of these conditions and their fatal prognosis. A panel of monoclonal and polyclonal antibodies have been generated for use in the study and diagnosis of these diseases. This manuscript describes the generation and characterization of these antibodies as well as their diagnostic application.

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Year:  1997        PMID： 9037628     DOI： 10.3109/08820139709048931

Source DB:  PubMed          Journal:  Immunol Invest        ISSN： 0882-0139            Impact factor:   3.657


  7 in total

1.  Coinfecting prion strains compete for a limiting cellular resource.

Authors:  Ronald A Shikiya; Jacob I Ayers; Charles R Schutt; Anthony E Kincaid; Jason C Bartz
Journal:  J Virol       Date:  2010-03-17       Impact factor: 5.103

2.  Infected splenic dendritic cells are sufficient for prion transmission to the CNS in mouse scrapie.

Authors:  P Aucouturier; F Geissmann; D Damotte; G P Saborio; H C Meeker; R Kascsak; R Kascsak; R I Carp; T Wisniewski
Journal:  J Clin Invest       Date:  2001-09       Impact factor: 14.808

3.  Chronic subclinical prion disease induced by low-dose inoculum.

Authors:  Alana M Thackray; Michael A Klein; Adriano Aguzzi; Raymond Bujdoso
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

4.  Immunization delays the onset of prion disease in mice.

Authors:  Einar M Sigurdsson; David R Brown; Maki Daniels; Richard J Kascsak; Regina Kascsak; Richard Carp; Harry C Meeker; Blas Frangione; Thomas Wisniewski
Journal:  Am J Pathol       Date:  2002-07       Impact factor: 4.307

5.  Direct detection of disease associated prions in brain and lymphoid tissue using antibodies recognizing the extreme N terminus of PrPC.

Authors:  Geoff Barnard; Lee Hopkins; Sowmiya Moorthie; David Seilly; Paul Tonks; Reza Dabaghian; Jonathan Clewley; John Coward; Ian McConnell
Journal:  Prion       Date:  2007-04-15       Impact factor: 3.931

6.  N(ε)-Carboxymethyl Modification of Lysine Residues in Pathogenic Prion Isoforms.

Authors:  Yeong-Gon Choi; Hae-Young Shin; Jae-Il Kim; Eun-Kyoung Choi; Richard I Carp; Yong-Sun Kim
Journal:  Mol Neurobiol       Date:  2015-05-16       Impact factor: 5.590

7.  Development of a Quantitative FMRP Assay for Mouse Tissue Applications.

Authors:  Tatyana Adayev; Giuseppe LaFauci; Weimin Xu; Carl Dobkin; Richard Kascsak; W Ted Brown; Jeffrey H Goodman
Journal:  Genes (Basel)       Date:  2021-09-26       Impact factor: 4.096
  7 in total

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