| Literature DB >> 9037604 |
P J Byrd, T Stankovic, C M McConville, A D Smith, P R Cooper, A M Taylor.
Abstract
We have localized the human homolog of the rabbit vasopressin-activated calcium-mobilizing receptor VACM-1 to a region close to the gene for ataxia telangiectasia ATM on chromosome 11q22-23. We have determined the complete amino acid sequence of the human Hs-VACM-1 protein, which is 780 amino acids long. The human and rabbit sequences are highly conserved, differing at only seven amino acids. Northern analysis of the human gene showed expression in a wide range of human tissues. The Hs-VACM-1 gene has homology with the Caenorhabditis elegans gene Ce-cul-5, a member of a family of cullin genes that are involved in cell cycle regulation and that might, when mutated, contribute to tumor progression.Entities:
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Year: 1997 PMID： 9037604 DOI： 10.1101/gr.7.1.71
Source DB: PubMed Journal: Genome Res ISSN： 1088-9051 Impact factor: 9.043