| Literature DB >> 9033589 |
L Szilák, J Moitra, D Krylov, C Vinson.
Abstract
Phosphorylation of threonine destabilizes the leucine zipper of a bZIP protein by 4.6 kcal mol-1 dimer-1, which reduces DNA binding 100-fold. This decrease in stability reflects the low alpha-helix forming propensity of a phosphorylated threonine.Entities:
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Year: 1997 PMID： 9033589 DOI： 10.1038/nsb0297-112
Source DB: PubMed Journal: Nat Struct Biol ISSN： 1072-8368