Literature DB >> 9033299

Gelatin-resorcinol-formaldehyde-glutaraldehyde glue-spread stapler prevents air leakage from the lung.

H Nomori1, H Horio.   

Abstract

BACKGROUND: To reinforce the staple line of the emphysematous lung and thereby prevent air leakage during thoracoscopic operations, we have developed a procedure of lung excision that uses a gelatin-resorcinol-formaldehyde-glutaraldehyde (GRFG) glue-spread stapler.
METHODS: Formaldehyde-glutaraldehyde (FG) jelly is prepared by mixing FG fluid with 2.5% sodium carboxymethyl cellulose. The FG jelly is placed in the stapler groove and staple holes, and a gelatin-resorcinol (GR) mixture is applied. The GRFG glue-spread stapler was applied to emphysematous lung cutting during thoracoscopic operations in 10 cases.
RESULTS: An adhesion-strength test showed no difference in glue adhesion between FG fluid and FG jelly. An experiment using swine lung showed that with this newly developed stapler, no resistance in firing occurred, and GRFG glue covered every staple hole. Clinical application in 10 cases with emphysematous lung demonstrated no air leakage from the staple line, even long after the operation.
CONCLUSIONS: Emphysematous lung excision using the GRFG glue-spread stapler during thoracoscopic operations is useful in preventing air leakage from the staple line and is a simple, safe, and low-cost procedure.

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Year:  1997        PMID: 9033299     DOI: 10.1016/s0003-4975(96)01020-x

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  4 in total

1.  [Video-assisted thoracoscopic surgery in spontaneous hemopneumothorax].

Authors:  H Horio; H Nomori; K Suemasu
Journal:  Jpn J Thorac Cardiovasc Surg       Date:  1998-10

Review 2.  Bioadhesives for musculoskeletal tissue regeneration.

Authors:  Solaiman Tarafder; Ga Young Park; Jeffrey Felix; Chang H Lee
Journal:  Acta Biomater       Date:  2020-10-06       Impact factor: 8.947

3.  The efficacy and side effects of gelatin-resorcinol formaldehyde-glutaraldehyde (GRFG) glue for preventing and sealing pulmonary air leakage.

Authors:  H Nomori; H Horio; K Suemasu
Journal:  Surg Today       Date:  2000       Impact factor: 2.549

Review 4.  Bridging wounds: tissue adhesives' essential mechanisms, synthesis and characterization, bioinspired adhesives and future perspectives.

Authors:  Kaige Xu; Xiaozhuo Wu; Xingying Zhang; Malcolm Xing
Journal:  Burns Trauma       Date:  2022-10-05
  4 in total

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