Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Reed-Sternberg cells and "bystander" lymphocytes in lymph nodes affected by Hodgkin's disease are infected with different strains of Epstein-Barr virus.

Literature DB >> 9032398

Reed-Sternberg cells and "bystander" lymphocytes in lymph nodes affected by Hodgkin's disease are infected with different strains of Epstein-Barr virus.

F Meggetto¹, P Brousset, J Selves, G Delsol, B Mariame.

Abstract

In most cases of Epstein-Barr virus (EBV)-associated Hodgkin's disease (HD), EBV-positive Reed-Sternberg (RS) cells and rare EBV-positive reservoir lymphocytes coexist in lymph nodes. Here we show that, in two cases of EBV-associated HD, strains infecting RS cells and reservoir lymphocytes of the same patient have different BNLF-1 genes. This suggests that RS cells and reservoir lymphocytes of the same patient are infected by different EBV strains.

Entities: Disease Species

Mesh：

Year: 1997 PMID： 9032398 PMCID： PMC191371

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

22 in total

1. Cycle sequencing protocol using deep VentR (exo-) DNA polymerase and reduced dNTP and [alpha-35S]dATP concentrations.

Authors: B Mariamé
Journal: Biotechniques Date: 1996-07 Impact factor: 1.993

2. DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

Authors: R Baer; A T Bankier; M D Biggin; P L Deininger; P J Farrell; T J Gibson; G Hatfull; G S Hudson; S C Satchwell; C Séguin
Journal: Nature Date: 1984 Jul 19-25 Impact factor: 49.962

3. Deletions within the LMP1 oncogene of Epstein-Barr virus are clustered in Hodgkin's disease and identical to those observed in nasopharyngeal carcinoma.

Authors: H Knecht; E Bachmann; P Brousset; K Sandvej; D Nadal; F Bachmann; B F Odermatt; G Delsol; G Pallesen
Journal: Blood Date: 1993-11-15 Impact factor: 22.113

4. Assessment of the methods for the detection of Epstein-Barr virus nucleic acids and related gene products in Hodgkin's disease.

Authors: P Brousset; F Meggetto; S Chittal; F Bibeau; J Arnaud; B Rubin; G Delsol
Journal: Lab Invest Date: 1993-10 Impact factor: 5.662

5. Sequence variation in the Epstein-Barr virus latent membrane protein 1.

Authors: W E Miller; R H Edwards; D M Walling; N Raab-Traub
Journal: J Gen Virol Date: 1994-10 Impact factor: 3.891

6. Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice.

Authors: J B Wilson; J L Bell; A J Levine
Journal: EMBO J Date: 1996-06-17 Impact factor: 11.598

7. Epstein-Barr virus intrastrain recombination in oral hairy leukoplakia.

Authors: D M Walling; N Raab-Traub
Journal: J Virol Date: 1994-12 Impact factor: 5.103

8. Persistence of the same viral strain in early and late relapses of Epstein-Barr virus-associated Hodgkin's disease.

Authors: P Brousset; D Schlaifer; F Meggetto; E Bachmann; S Rothenberger; J Pris; G Delsol; H Knecht
Journal: Blood Date: 1994-10-15 Impact factor: 22.113

9. Epstein-Barr virus (EBV)-associated lymphoproliferations in severe combined immunodeficient mice transplanted with Hodgkin's disease lymph nodes: implications of EBV-positive bystander B lymphocytes rather than EBV-infected Reed-Sternberg cells.

Authors: F Meggetto; C Muller; S Henry; J Selves; B Mariamé; P Brousset; T A Saati; G Delsol
Journal: Blood Date: 1996-03-15 Impact factor: 22.113

Reed-Sternberg cells and "bystander" lymphocytes in lymph nodes affected by Hodgkin's disease are infected with different strains of Epstein-Barr virus.

1. Cycle sequencing protocol using deep VentR (exo-) DNA polymerase and reduced dNTP and [alpha-35S]dATP concentrations.

2. DNA sequence and expression of the B95-8 Epstein-Barr virus genome.

3. Deletions within the LMP1 oncogene of Epstein-Barr virus are clustered in Hodgkin's disease and identical to those observed in nasopharyngeal carcinoma.

4. Assessment of the methods for the detection of Epstein-Barr virus nucleic acids and related gene products in Hodgkin's disease.

5. Sequence variation in the Epstein-Barr virus latent membrane protein 1.

6. Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic mice.

7. Epstein-Barr virus intrastrain recombination in oral hairy leukoplakia.

8. Persistence of the same viral strain in early and late relapses of Epstein-Barr virus-associated Hodgkin's disease.

9. Epstein-Barr virus (EBV)-associated lymphoproliferations in severe combined immunodeficient mice transplanted with Hodgkin's disease lymph nodes: implications of EBV-positive bystander B lymphocytes rather than EBV-infected Reed-Sternberg cells.

10. Detection of Epstein-Barr virus in multiple sites involved by Hodgkin's disease.

1. Sequence variations of Epstein-Barr virus LMP1 gene in nasal NK/T-cell lymphoma.

2. Association of Hodgkin's lymphoma with Epstein Barr virus infection.

3. Evidence for early infection of nonneoplastic natural killer cells by Epstein-Barr virus.

4. Potential selection of LMP1 variants in nasopharyngeal carcinoma.

5. Detection of oncogenic virus genomes and gene products in lung carcinoma.