Literature DB >> 9032079

Not just another Fab: the crystal structure of a TcR-MHC-peptide complex.

T Jardetzky1.   

Abstract

The structure of a ternary complex formed between a T-cell receptor, a major histocompatibility complex (MHC) protein and a viral peptide provides new insights into the cellular immune response. The results provide a molecular basis for understanding the development of T cells and the reactions leading to transplant rejection and autoimmunity.

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Year:  1997        PMID: 9032079     DOI: 10.1016/s0969-2126(97)00175-5

Source DB:  PubMed          Journal:  Structure        ISSN: 0969-2126            Impact factor:   5.006


  5 in total

1.  Interpretation of biphasic dissociation kinetics for isomeric class II major histocompatibility complex-peptide complexes.

Authors:  T G Anderson; H M McConnell
Journal:  Biophys J       Date:  1999-11       Impact factor: 4.033

2.  Redundancy and Complementarity between ERAP1 and ERAP2 Revealed by their Effects on the Behcet's Disease-associated HLA-B*51 Peptidome.

Authors:  Pablo Guasp; Elena Lorente; Adrian Martín-Esteban; Eilon Barnea; Paolo Romania; Doriana Fruci; JonasJ W Kuiper; Arie Admon; José A López de Castro
Journal:  Mol Cell Proteomics       Date:  2019-05-15       Impact factor: 5.911

Review 3.  How ERAP1 and ERAP2 Shape the Peptidomes of Disease-Associated MHC-I Proteins.

Authors:  José A López de Castro
Journal:  Front Immunol       Date:  2018-10-30       Impact factor: 7.561

Review 4.  Medawar's legacy to cellular immunology and clinical transplantation: a commentary on Billingham, Brent and Medawar (1956) 'Quantitative studies on tissue transplantation immunity. III. Actively acquired tolerance'.

Authors:  Elizabeth Simpson
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-04-19       Impact factor: 6.237

Review 5.  Understanding the Pathogenesis of Spondyloarthritis.

Authors:  Aigul Sharip; Jeannette Kunz
Journal:  Biomolecules       Date:  2020-10-20
  5 in total

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