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Literature DB >> 9032066

Nucleation mechanisms in protein folding.

Abstract

Experiment and theory are converging on the importance of nucleation mechanisms in protein folding. These mechanisms do not use classic nuclei, which are well formed elements of structure present in ground states, but they use diffuse, extended regions, which are observed in transition states.

Mesh：

Year: 1997 PMID： 9032066 DOI： 10.1016/s0959-440x(97)80002-4

Source DB: PubMed Journal: Curr Opin Struct Biol ISSN： 0959-440X Impact factor: 6.809

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Cited

105 in total

Review 1. Folding funnels, binding funnels, and protein function.

Authors: C J Tsai; S Kumar; B Ma; R Nussinov
Journal: Protein Sci Date: 1999-06 Impact factor: 6.725

2. Deciphering the folding kinetics of transmembrane helical proteins.

Authors: E Orlandini; F Seno; J R Banavar; A Laio; A Maritan
Journal: Proc Natl Acad Sci U S A Date: 2000-12-19 Impact factor: 11.205

3. An amino acid code for protein folding.

Authors: J Rumbley; L Hoang; L Mayne; S W Englander
Journal: Proc Natl Acad Sci U S A Date: 2001-01-02 Impact factor: 11.205

4. A theoretical search for folding/unfolding nuclei in three-dimensional protein structures.

Authors: O V Galzitskaya; A V Finkelstein
Journal: Proc Natl Acad Sci U S A Date: 1999-09-28 Impact factor: 11.205

5. Transition-state structure as a unifying basis in protein-folding mechanisms: contact order, chain topology, stability, and the extended nucleus mechanism.

Authors: A R Fersht
Journal: Proc Natl Acad Sci U S A Date: 2000-02-15 Impact factor: 11.205

10. NMR and SAXS characterization of the denatured state of the chemotactic protein CheY: implications for protein folding initiation.

Authors: P Garcia; L Serrano; D Durand; M Rico; M Bruix
Journal: Protein Sci Date: 2001-06 Impact factor: 6.725

Nucleation mechanisms in protein folding.

Review 1. Folding funnels, binding funnels, and protein function.

2. Deciphering the folding kinetics of transmembrane helical proteins.

3. An amino acid code for protein folding.

4. A theoretical search for folding/unfolding nuclei in three-dimensional protein structures.

5. Transition-state structure as a unifying basis in protein-folding mechanisms: contact order, chain topology, stability, and the extended nucleus mechanism.

6. Protein folding and unfolding on a complex energy landscape.

7. The topomer-sampling model of protein folding.

8. Folding of a three-stranded coiled coil.

9. Unspecific hydrophobic stabilization of folding transition states.

10. NMR and SAXS characterization of the denatured state of the chemotactic protein CheY: implications for protein folding initiation.