Literature DB >> 9031876

In vitro study of the potential role of quinupristin/dalfopristin in the treatment of catheter-related staphylococcal infections.

R Garcia1, I Raad.   

Abstract

The susceptibility of clinical isolates of methicillin-susceptible and -resistant staphylococci from cancer patients with central venous catheter bacteremia to quinupristin/dalfopristin, a semisynthetic streptogramin, was determined in vitro. Susceptibility of these isolates to nine other antistaphylococcal antibiotics was also determined for comparison. A total of 197 staphylococcal strains were tested from 1983 to 1992. Quinupristin/dalfopristin was bactericidal against all isolates, independent of their resistance to methicillin. Its activity was similar to that of vancomycin but superior to that of teicoplanin. Quinupristin/dalfopristin may prove to be an important addition to our armamentarium against catheter-related staphylococcal infections.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 9031876     DOI： 10.1007/bf01690511

Source DB:  PubMed          Journal:  Eur J Clin Microbiol Infect Dis        ISSN： 0934-9723            Impact factor:   3.267


  15 in total

1.  In-vitro activity of RP 59500, a semisynthetic streptogramin, against staphylococci and streptococci.

Authors:  J C Pechère
Journal:  J Antimicrob Chemother       Date:  1992-07       Impact factor: 5.790

Review 2.  Infectious complications of indwelling vascular catheters.

Authors:  I I Raad; G P Bodey
Journal:  Clin Infect Dis       Date:  1992-08       Impact factor: 9.079

Review 3.  Coagulase-negative staphylococci. Epidemiology, evaluation, and therapy.

Authors:  D A Nafziger; R P Wenzel
Journal:  Infect Dis Clin North Am       Date:  1989-12       Impact factor: 5.982

4.  Evolution and present situation of Staphylococcus aureus sensitivity to MLS in hospital (1975-83).

Authors:  A Thabaut; M Meyran; M Huerre
Journal:  J Antimicrob Chemother       Date:  1985-07       Impact factor: 5.790

5.  Emergence of vancomycin resistance in coagulase-negative staphylococci.

Authors:  R S Schwalbe; J T Stapleton; P H Gilligan
Journal:  N Engl J Med       Date:  1987-04-09       Impact factor: 91.245

Review 6.  Bacterial biofilms in nature and disease.

Authors:  J W Costerton; K J Cheng; G G Geesey; T I Ladd; J C Nickel; M Dasgupta; T J Marrie
Journal:  Annu Rev Microbiol       Date:  1987       Impact factor: 15.500

7.  Staphylococcus epidermidis extracted slime inhibits the antimicrobial action of glycopeptide antibiotics.

Authors:  B F Farber; M H Kaplan; A G Clogston
Journal:  J Infect Dis       Date:  1990-01       Impact factor: 5.226

8.  In vitro activity of RP59500, an injectable streptogramin antibiotic, against vancomycin-resistant gram-positive organisms.

Authors:  L A Collins; G J Malanoski; G M Eliopoulos; C B Wennersten; M J Ferraro; R C Moellering
Journal:  Antimicrob Agents Chemother       Date:  1993-03       Impact factor: 5.191

9.  In-vitro activity of RP 59500, a new semisynthetic streptogramin antibiotic, against gram-positive bacteria.

Authors:  W Brumfitt; J M Hamilton-Miller; S Shah
Journal:  J Antimicrob Chemother       Date:  1992-07       Impact factor: 5.790

10.  Antimicrobial activity against Staphylococcus aureus of semisynthetic injectable streptogramins: RP 59500 and related compounds.

Authors:  J C Barrière; D H Bouanchaud; J M Paris; O Rolin; N V Harris; C Smith
Journal:  J Antimicrob Chemother       Date:  1992-07       Impact factor: 5.790
View more
  1 in total

Review 1.  Quinupristin/dalfopristin: a review of its use in the management of serious gram-positive infections.

Authors:  H M Lamb; D P Figgitt; D Faulds
Journal:  Drugs       Date:  1999-12       Impact factor: 9.546
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.