Literature DB >> 9031625

Cloning and characterization of Chinese hamster p53 cDNA.

H Lee1, J M Larner, J L Hamlin.   

Abstract

We have cloned and sequenced Chinese hamster p53 cDNA and have compared the p53 sequence in different Chinese hamster cell lines to several relevant phenotypes. Our results indicate that a mutation in CHO cells that changes Thr211 to Lys211 abrogates the ability to arrest in G1 and apparently renders cells capable of amplifying DNA. However, this mutation has no effect on the G2 checkpoint or on acute down-regulation of DNA replication after a radiation challenge.

Entities:  

Mesh：

Substances：

Year:  1997        PMID： 9031625     DOI： 10.1016/s0378-1119(96)00592-6

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  11 in total

1.  UV-induced but P53 independent apoptotic death in CHO.K1 cells is promoted by M phase inhibitors.

Authors:  B S Tzang; Y C Lai; Y C Liu
Journal:  In Vitro Cell Dev Biol Anim       Date:  1999-01       Impact factor: 2.416

2.  Transcription-coupled repair is inducible in hamster cells.

Authors:  M Germanier; M Defais; V A Bohr; F Larminat
Journal:  Nucleic Acids Res       Date:  2000-12-01       Impact factor: 16.971

3.  Cell proliferation and DNA breaks are involved in ultraviolet light-induced apoptosis in nucleotide excision repair-deficient Chinese hamster cells.

Authors:  Torsten R Dunkern; Bernd Kaina
Journal:  Mol Biol Cell       Date:  2002-01       Impact factor: 4.138

4.  Growth inhibition by the muscarinic M(3) acetylcholine receptor: evidence for p21(Cip1/Waf1) involvement in G(1) arrest.

Authors:  Drew Burdon; Rajnikant Patel; R A John Challiss; Jonathan L Blank
Journal:  Biochem J       Date:  2002-10-15       Impact factor: 3.857

5.  Influence of homologous recombinational repair on cell survival and chromosomal aberration induction during the cell cycle in gamma-irradiated CHO cells.

Authors:  Paul F Wilson; John M Hinz; Salustra S Urbin; Peter B Nham; Larry H Thompson
Journal:  DNA Repair (Amst)       Date:  2010-07-01

6.  Condensation by DNA looping facilitates transfer of large DNA molecules into mammalian cells.

Authors:  W J Montigny; C R Houchens; S Illenye; J Gilbert; E Coonrod; Y C Chang; N H Heintz
Journal:  Nucleic Acids Res       Date:  2001-05-01       Impact factor: 16.971

7.  Ubiquitylation, phosphorylation and Orc2 modulate the subcellular location of Orc1 and prevent it from inducing apoptosis.

Authors:  Tapas Saha; Soma Ghosh; Alex Vassilev; Melvin L DePamphilis
Journal:  J Cell Sci       Date:  2006-03-14       Impact factor: 5.285

8.  p53 protein is a suppressor of papillomavirus DNA amplificational replication.

Authors:  D Lepik; I Ilves; A Kristjuhan; T Maimets; M Ustav
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

Review 9.  Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: mechanistic insights.

Authors:  Larry H Thompson; John M Hinz
Journal:  Mutat Res       Date:  2009-02-21       Impact factor: 2.433

10.  Genotoxic and cytotoxic effects of 60Co gamma-rays and 90Sr/90Y beta-rays on Chinese hamster ovary cells (CHO-K1).

Authors:  Daniella Murakami; Miriam Fussae Suzuki; Mauro da Silva Dias; Kayo Okazaki
Journal:  Radiat Environ Biophys       Date:  2004-05-11       Impact factor: 1.925
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.