Literature DB >> 9031095

Occurrence of myeloma in a chronic lymphocytic leukemia patients after response to differentiation therapy with interleukin-4.

D Makower1, U Venkatraj, J P Dutcher, P H Wiernik.   

Abstract

The occurrence of chronic lymphocytic leukemia (CLL) and multiple myeloma (MM) in a single individual is rare, and the clonal relationship between the two neoplasms is unclear. We describe here a patient with CLL who developed symptoms of MM while responding to experimental therapy with interleukin-4 (IL-4). This patient was treated with 2-chlorodeoxyadenosine (2-CDA), and had a response in both malignancies.

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Year:  1996        PMID： 9031095     DOI： 10.3109/10428199609054873

Source DB:  PubMed          Journal:  Leuk Lymphoma        ISSN： 1026-8022


  4 in total

1.  Phase II study of interleukin-4 in indolent B-cell non-Hodgkin lymphoma and B-cell chronic lymphocytic leukemia: a study of the Eastern Cooperative Oncology Group (E5Y92).

Authors:  Peter H Wiernik; Janice P Dutcher; Xiapan Yao; Usha Venkatraj; Carla I Falkson; Jacob M Rowe; Peter A Cassileth
Journal:  J Immunother       Date:  2010 Nov-Dec       Impact factor: 4.456

Review 2.  Treatment of hematologic neoplasms with new immunomodulatory drugs (IMiDs).

Authors:  Peter H Wiernik
Journal:  Curr Treat Options Oncol       Date:  2008-11-19

3.  Acute B Lymphoblastic Leukemia Developing in Patients with Multiple Myeloma: Presentation of Two Cases

Authors:  Jiang Mei; Li Na; Ji Dexiang; Li Fei; Zhang Zhanglin
Journal:  Turk J Haematol       Date:  2019-06-25       Impact factor: 1.831

Review 4.  Second neoplasms in patients with chronic lymphocytic leukemia.

Authors:  Peter H Wiernik
Journal:  Curr Treat Options Oncol       Date:  2004-06
  4 in total

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