Management of clusters of meningococcal disease. PHIS Meningococcus Working Group and Public Health Medicine Environmental Group.

Guidance on the management of clustered cases of meningococcal disease has been revised following a review of the clusters that occurred in England and Wales between 1 April 1995 and 31 March 1996. Public health action is indicated for confirmed and probable cases but not in response to possible cases. The importance of microbiological confirmation is re-emphasised. Intervention is recommended for defined target groups when two or more confirmed or probable cases occur in a preschool group or school within a four week period. We present a framework to assist in the management of clusters of invasive serogroup C infections in larger and less defined communities.