Literature DB >> 902661

Uric acid infarctions in the kidneys of newborn infants. A study on the changing incidence and on oxypurine ratios.

H Manzke, G Eigster, D Harms, K Dörner, J Grünitz.   

Abstract

Among 1115 newborns who died during 1957--1976, 136 (12.2%) showed macroscopic renal uric acid infarctions. The incidence depended on the age of the infants and their fluid supply during the first days of life. After introduction of parenteral alkali-glucose infusion in the treatment of perinatal complications, the incidence of renal uric acid infarctions decreased from 19.3% to less than 1.0%. Analysis of the oxypurines in the renal uric acid infarctions of three newborns revealed high percentages of hypoxanthine (31.1%, 21.8% and 11.0%) along with the uric acid. Hypoxanthine ratios above 15% retrospectively point to chronic hypoxia of the newborn.

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Year:  1977        PMID： 902661     DOI： 10.1007/bf00443120

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  8 in total

1.  EFFECT OF ISCHEMIA ON ADENINE NUCLEOTIDES IN CARDIAC AND SKELETAL MUSCLE.

Authors:  S IMAI; A L RILEY; R M BERNE
Journal:  Circ Res       Date:  1964-11       Impact factor: 17.367

2.  [Results of histochemical studies on so-called uric acid infarct of the kidneys].

Authors:  W R HERRMANN
Journal:  Virchows Arch Pathol Anat Physiol Klin Med       Date:  1963

3.  Hypoxanthine as a measurement of hypoxia.

Authors:  O D Saugstad
Journal:  Pediatr Res       Date:  1975-04       Impact factor: 3.756

4.  Urinary hypoxanthine, xanthine and uric acid excretion in newborn infants with perinatal complications.

Authors:  H Manzke; K Dörner; J Grünitz
Journal:  Acta Paediatr Scand       Date:  1977-11

5.  Concentrations of uric acid in the serum of neonatal infants and their mothers.

Authors:  E S Monkus; W L Nyhan; B J Fogel; S Yankow
Journal:  Am J Obstet Gynecol       Date:  1970-09-01       Impact factor: 8.661

6.  [Simple determination of purines by preparative thin-layer chromatography].

Authors:  K Dörner; H Manzke
Journal:  Z Klin Chem Klin Biochem       Date:  1971-01

7.  [Increased hypoxanthine, creatinine and alpha fetoprotein excretion in urine of newborn infants with birth complications].

Authors:  H Manzke; K Dörner; J Grünitz; H Anger; H Wensky
Journal:  Monatsschr Kinderheilkd       Date:  1976-05

8.  Neonatal hyperuricemia.

Authors:  K O Raivio
Journal:  J Pediatr       Date:  1976-04       Impact factor: 4.406
  8 in total
  2 in total

1.  Quantitative measurements of the urinary excretion of creatinine, uric acid, hypoxanthine and xanthine, uracil, cyclic AMP, and cyclic GMP in healthy newborn infants.

Authors:  H Manzke; P Spreter von Kreudenstein; K Dörner; K Kruse
Journal:  Eur J Pediatr       Date:  1980-03       Impact factor: 3.183

Review 2.  Acute renal failure in neonates: incidence, etiology and outcome.

Authors:  F B Stapleton; D P Jones; R S Green
Journal:  Pediatr Nephrol       Date:  1987-07       Impact factor: 3.714
  2 in total

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