Literature DB >> 9025232

Probing the dynamics of prion diseases with amphotericin B.

K T Adjou1, J P Deslys, R Demaimay, D Dormont.   

Abstract

Amphotericin B (AmB) is one of the rare drugs that affect the course of experimental prion diseases and modify the kinetics of abnormal prion protein accumulation in the central nervous system. Therefore, AmB could be used as a pharmacological tool to contribute to our understanding of the pathogenic mechanisms involved in these neurodegenerative disorders.

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Year:  1997        PMID: 9025232     DOI: 10.1016/S0966-842X(97)81771-4

Source DB:  PubMed          Journal:  Trends Microbiol        ISSN: 0966-842X            Impact factor:   17.079


  7 in total

Review 1.  Prion diseases: current understanding of epidemiology and pathogenesis, and therapeutic advances.

Authors:  Maria Caramelli; Giuseppe Ru; Pierluigi Acutis; Gianluigi Forloni
Journal:  CNS Drugs       Date:  2006       Impact factor: 5.749

2.  Orally administered amyloidophilic compound is effective in prolonging the incubation periods of animals cerebrally infected with prion diseases in a prion strain-dependent manner.

Authors:  Yuri Kawasaki; Keiichi Kawagoe; Chun-jen Chen; Kenta Teruya; Yuji Sakasegawa; Katsumi Doh-ura
Journal:  J Virol       Date:  2007-09-19       Impact factor: 5.103

3.  A sensitive amphotericin B immunoassay for pharmacokinetic and distribution studies.

Authors:  S Machard; F Theodoro; H Benech; J M Grognet; E Ezan
Journal:  Antimicrob Agents Chemother       Date:  2000-03       Impact factor: 5.191

Review 4.  Prions: Beyond a Single Protein.

Authors:  Alvin S Das; Wen-Quan Zou
Journal:  Clin Microbiol Rev       Date:  2016-07       Impact factor: 26.132

5.  Effects of the polyene antibiotic derivative MS-8209 on the astrocyte lysosomal system of scrapie-infected hamsters.

Authors:  Vladimir B Grigoriev; Karim T Adjou; Nicole Salès; Steve Simoneau; Jean-Philippe Deslys; Michel Seman; Dominique Dormont; Jean-Guy Fournier
Journal:  J Mol Neurosci       Date:  2002-06       Impact factor: 3.444

Review 6.  The impact of antifungals on toll-like receptors.

Authors:  Mircea R Mihu; Rodney Pattabhi; Joshua D Nosanchuk
Journal:  Front Microbiol       Date:  2014-03-14       Impact factor: 5.640

Review 7.  Prion protein misfolding.

Authors:  L Kupfer; W Hinrichs; M H Groschup
Journal:  Curr Mol Med       Date:  2009-09       Impact factor: 2.222

  7 in total

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