Literature DB >> 9024742

Blockade of K(ATP) channels with glibenclamide does not abolish preconditioning during demand ischemia.

S D Correa1, S Schaefer.   

Abstract

The role of adenosine triphosphate-sensitive potassium channels in the adaptive response to demand ischemia was tested in 22 patients treated with placebo or glibenclamide before sequential exercise testing or atrial pacing. Glibenclamide did not affect the improvement in signs of ischemia in both protocols, indicating that opening of these channels is not a mechanism of this adaptive response in humans.

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Year:  1997        PMID: 9024742     DOI: 10.1016/s0002-9149(96)00681-9

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  6 in total

1.  Warm up phenomenon and preconditioning in clinical practice.

Authors:  F Tomai
Journal:  Heart       Date:  2002-02       Impact factor: 5.994

Review 2.  Is impairment of ischaemic preconditioning by sulfonylurea drugs clinically important?

Authors:  J J Meier; B Gallwitz; W E Schmidt; A Mügge; M A Nauck
Journal:  Heart       Date:  2004-01       Impact factor: 5.994

3.  Does a selective adenosine A(1) receptor agonist protect against exercise induced ischaemia in patients with coronary artery disease?

Authors:  A D Kelion; T P Webb; M A Gardner; O J Ormerod; G L Shepherd; A P Banning
Journal:  Heart       Date:  2002-02       Impact factor: 5.994

4.  Antiarrhythmic and anti-ischaemic effects of angina in patients with and without coronary collaterals.

Authors:  R J Edwards; S R Redwood; P D Lambiase; E Tomset; R D Rakhit; M S Marber
Journal:  Heart       Date:  2002-12       Impact factor: 5.994

Review 5.  Pro- and Antiarrhythmic Actions of Sulfonylureas: Mechanistic and Clinical Evidence.

Authors:  Charles E Leonard; Sean Hennessy; Xu Han; David S Siscovick; James H Flory; Rajat Deo
Journal:  Trends Endocrinol Metab       Date:  2017-05-22       Impact factor: 12.015

Review 6.  Impact of hypoglycemic agents on myocardial ischemic preconditioning.

Authors:  Rosa Maria Rahmi Garcia; Paulo Cury Rezende; Whady Hueb
Journal:  World J Diabetes       Date:  2014-06-15
  6 in total

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