| Literature DB >> 9024627 |
M R Lieber1, U Grawunder, X Wu, M Yaneva.
Abstract
A convergence of information from biochemistry, yeast and mammalian genetics, immunology, and radiation biology has permitted identification of some of the protein participants - Ku, DNA-PK, XRCC4 - and the reaction intermediates in DNA end joining, suggesting how broken chromosomal ends may be recognized and repaired in eukaryotic cells. Some components may be defective in inherited disorders.Entities:
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Year: 1997 PMID： 9024627 DOI： 10.1016/s0959-437x(97)80116-5
Source DB: PubMed Journal: Curr Opin Genet Dev ISSN： 0959-437X Impact factor: 5.578