Literature DB >> 9023977

Heterocyclic analogues of quinone methide: preparation and cytotoxicity of 3-oxo-3H-pyrazolo[1,5-a]indole derivatives.

H Katayama1, N Tagawa, Y Kawada, K Shiobara, K Kaneko, Y Honda, N Kondo, Y Ikeda.   

Abstract

A series of 3-oxo-3H-pyrazolo[1,5-a]indole derivatives was prepared and characterized as heterocyclic analogues of quinone methide. These compounds showed some cytotoxicity to cancer cells, but were ineffective in an in vivo test against murine leukemia L1210.

Entities:  

Mesh:

Substances:

Year:  1997        PMID: 9023977     DOI: 10.1248/cpb.45.143

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Cytotoxic activities and DNA binding properties of 1-methyl-7H-indeno[1,2-b]quinolinium-7-(4-dimethylamino) benzylidene triflate.

Authors:  Wen Li; Yuan Yuan Ji; Jian Wen Wang; Yong Ming Zhu
Journal:  DNA Cell Biol       Date:  2012-01-25       Impact factor: 3.311

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.