Literature DB >> 902231

Antibody-dependent cell-mediated cytotoxicity in treated and nontreated cancer patients.

M L Stratton, J Herz, R A Loeffler, F L McClurg, A Reiter, P Bernstein, D L Danley, E Benjamini.   

Abstract

Antibody-dependent cell-mediated cytotoxicity (ADCC) exhibited by peripheral blood leukocytes was used as a criterion for assessing immune competence of groups of noncancerous individuals and of treated and untreated cancer patients. The results show that, as a group, leukocytes of nontreated cancer patients exhibited significantly lower ADCC than that exhibited by leukocytes of noncancerous individuals. However, the ADCC of leukocytes from cancer patients under treatment approximated that of normals. Thus, using ADCC as criterion, the results indicate that as a group, cancer patients under treatment tend to exhibit restored immune competence.

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Year:  1977        PMID: 902231     DOI: 10.1002/1097-0142(197709)40:3<1045::aid-cncr2820400312>3.0.co;2-b

Source DB:  PubMed          Journal:  Cancer        ISSN: 0008-543X            Impact factor:   6.860


  7 in total

1.  Natural killer and antibody-dependent cellular cytotoxicity in cervical carcinoma patients.

Authors:  M N Satam; J N Suraiya; J J Nadkarni
Journal:  Cancer Immunol Immunother       Date:  1986       Impact factor: 6.968

2.  Approach to the radiosensitivity of antibody dependent cellular cytotoxicity.

Authors:  D Dormont; B Coupez; F Herodin; N Delasnerie-Laupretre; A Bohu; C Pasquier
Journal:  Br J Cancer Suppl       Date:  1986

3.  Influence of non-specific immunologic factors on prognosis in advanced bronchogenic carcinoma.

Authors:  A M Liberati; J G Voelkel; E C Borden; A S Coates; D L Citrin; G T Bryan
Journal:  Cancer Immunol Immunother       Date:  1982       Impact factor: 6.968

4.  Decreased monocyte antibody-dependent cell-mediated toxicity in stage I-II malignant melanoma. Augmentation by subcutaneous Corynebacterium parvum.

Authors:  J L Murray; E T Lee
Journal:  Cancer Immunol Immunother       Date:  1984       Impact factor: 6.968

5.  Antibody-dependent and spontaneous lympholysis in urologic cancer patients.

Authors:  T L Ratliff; R E McCool; W J Catalona
Journal:  Br J Cancer       Date:  1979-06       Impact factor: 7.640

6.  Antibody-dependent cellular cytotoxicity in cancer patients: lack of prognostic value.

Authors:  J A McCredie; H R MacDonald
Journal:  Br J Cancer       Date:  1980-06       Impact factor: 7.640

7.  m17-1A-, c17-1A- and cSF25-mediated antibody-dependent cell-mediated cytotoxicity in patients with advanced cancer.

Authors:  A M Pullyblank; P J Guillou; J R Monson
Journal:  Br J Cancer       Date:  1994-10       Impact factor: 7.640

  7 in total

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