Literature DB >> 9020063

Genomic structure and promoter characterization of the human ACTH receptor gene.

D Naville1, C Jaillard, L Barjhoux, P Durand, M Bégeot.   

Abstract

One kb of the 5'-flanking region of the human ACTH receptor gene was isolated and partially characterized. Transient transfections with hGH reporter confirmed the promoter activity in Y1 cells. Putative elements for transcription factors involved in regulation were noted in the sequence. The promoter activity of some of the constructs is responsive to a treatment by forskolin, due to the presence of several CRE-like sequences.

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Year:  1997        PMID: 9020063     DOI: 10.1006/bbrc.1996.5911

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  4 in total

Review 1.  Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment.

Authors:  Vadim Yuferov; Orna Levran; Dmitri Proudnikov; David A Nielsen; Mary Jeanne Kreek
Journal:  Ann N Y Acad Sci       Date:  2010-02       Impact factor: 5.691

2.  Expression of adrenocorticotropin receptor gene in adrenocortical adenomas from patients with Cushing syndrome: possible contribution for the autonomous production of cortisol.

Authors:  T Imai; D Sarkar; A Shibata; H Funahashi; T Morita-Matsuyama; T Kikumori; S Ohmori; H Seo
Journal:  Ann Surg       Date:  2001-07       Impact factor: 12.969

3.  Association of polymorphisms in the melanocortin receptor type 2 (MC2R, ACTH receptor) gene with heroin addiction.

Authors:  Dmitri Proudnikov; Sara Hamon; Jurg Ott; Mary Jeanne Kreek
Journal:  Neurosci Lett       Date:  2008-02-26       Impact factor: 3.046

4.  Characterization of novel StAR (steroidogenic acute regulatory protein) mutations causing non-classic lipoid adrenal hyperplasia.

Authors:  Christa E Flück; Amit V Pandey; Bernhard Dick; Núria Camats; Mónica Fernández-Cancio; María Clemente; Miquel Gussinyé; Antonio Carrascosa; Primus E Mullis; Laura Audi
Journal:  PLoS One       Date:  2011-05-27       Impact factor: 3.240

  4 in total

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