Literature DB >> 9020020

Telomere crisis, the driving force in cancer cell evolution.

F Ishikawa1.   

Abstract

Cancer cells show characteristic telomere dynamics. Their chromosomes usually have short telomeres and a high telomerase activity. The "telomere crisis model" proposed here suggests that these unique telomeric features are responsible for the progression of cancer.

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Year:  1997        PMID： 9020020     DOI： 10.1006/bbrc.1996.5928

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Improved in situ detection method for telomeric tandem repeats in metaphase spreads and interphase nuclei.

Authors:  V Uhlmann; M Prasad; I Silva; K Luettich; L Grande; L Alonso; M Thisted; K J Pluzek; J Gorst; M Ring; M Sweeney; C Kenny; C Martin; J Russell; N Bermingham; M O'Donovan; O Sheils; J J O'Leary
Journal:  Mol Pathol       Date:  2000-02

2.  Telomere, telomerase and digestive cancer.

Authors:  Javed Yakoob; Guo-Ling Hu; Xue-Gong Fan; Zheng Zhang
Journal:  World J Gastroenterol       Date:  1999-08       Impact factor: 5.742

3.  Growth inhibition of human glioma cells by transfection-induced P21 and its effects on telomerase activity.

Authors:  K Harada; K Kurisu; T Sadatomo; H Tahara; E Tahara; T Ide; E Tahara
Journal:  J Neurooncol       Date:  2000-03       Impact factor: 4.130

4.  Telomere loss in cells treated with cisplatin.

Authors:  T Ishibashi; S J Lippard
Journal:  Proc Natl Acad Sci U S A       Date:  1998-04-14       Impact factor: 11.205

5.  Involvement of WRN helicase in immortalization and tumorigenesis by the telomeric crisis pathway (Review).

Authors:  Masanobu Sugimoto; Yasuhiro Furuichi; Toshinori Ide; Makoto Goto
Journal:  Oncol Lett       Date:  2011-05-06       Impact factor: 2.967

6.  Frequent somatic mutations of the telomerase reverse transcriptase promoter in ovarian clear cell carcinoma but not in other major types of gynaecological malignancy.

Authors:  Ren-Chin Wu; Ayse Ayhan; Daichi Maeda; Kyu-Rae Kim; Blaise A Clarke; Patricia Shaw; Michael Herman Chui; Barry Rosen; Ie-Ming Shih; Tian-Li Wang
Journal:  J Pathol       Date:  2014-03       Impact factor: 7.996

7.  Up-regulation of telomere-binding proteins, TRF1, TRF2, and TIN2 is related to telomere shortening during human multistep hepatocarcinogenesis.

Authors:  Bong-Kyeong Oh; Young-Joo Kim; Chanil Park; Young Nyun Park
Journal:  Am J Pathol       Date:  2005-01       Impact factor: 4.307

8.  Stable karyotypes in epithelial cancer cell lines despite high rates of ongoing structural and numerical chromosomal instability.

Authors:  Anna V Roschke; Kristen Stover; Giovanni Tonon; Alejandro A Schäffer; Ilan R Kirsch
Journal:  Neoplasia       Date:  2002 Jan-Feb       Impact factor: 5.715

9.  High telomerase activity correlates with the stabilities of genome and DNA ploidy in renal cell carcinoma.

Authors:  Hideki Izumi; Takahiko Hara; Atsunori Oga; Kenji Matsuda; Yuko Sato; Katsusuke Naito; Kohsuke Sasaki
Journal:  Neoplasia       Date:  2002 Mar-Apr       Impact factor: 5.715

10.  Telomerase expression is sufficient for chromosomal integrity in cells lacking p53 dependent G1 checkpoint function.

Authors:  Dennis A Simpson; Elizabeth Livanos; Timothy P Heffernan; William K Kaufmann
Journal:  J Carcinog       Date:  2005-10-06
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