Literature DB >> 9018090

Micronuclei-induction and its correlation to cell survival in HeLa cells treated with different doses of adriamycin.

G C Jagetia1, V Nayak.   

Abstract

The treatment of HeLa cells with different concentrations of adriamycin (0, 5, 10, 25, 50 and 100 microg/ml) resulted in a significant and dose-dependent decline in the cell survival. Conversely, the frequency of micronuclei increased in a concentration-dependent manner. The micronuclei-induction and cell survival were found to be inversely related.

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Year:  1996        PMID： 9018090     DOI： 10.1016/s0304-3835(96)04470-9

Source DB:  PubMed          Journal:  Cancer Lett        ISSN： 0304-3835            Impact factor:   8.679


  2 in total

1.  Evaluation of the mutagenicity and antimutagenicity of Ziziphus joazeiro Mart. bark in the micronucleus assay.

Authors:  Marcelo Fabiano Gomes Boriollo; Marielly Reis Resende; Thaísla Andrielle da Silva; Juliana Yoshida Públio; Luiz Silva Souza; Carlos Tadeu Dos Santos Dias; Nelma de Mello Silva Oliveira; João Evangelista Fiorini
Journal:  Genet Mol Biol       Date:  2014-06       Impact factor: 1.771

2.  Combined study on clastogenic, aneugenic and apoptotic properties of doxorubicin in human cells in vitro.

Authors:  Vasiliki Chondrou; Katerina Trochoutsou; Andreas Panayides; Maria Efthimiou; Georgia Stephanou; Nikos A Demopoulos
Journal:  J Biol Res (Thessalon)       Date:  2018-10-11       Impact factor: 1.889
  2 in total

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