Literature DB >> 9015793

Replicating viruses as selective cancer therapeutics.

D H Kirn1, F McCormick.   

Abstract

Replication-competent viruses are used as selective cancer therapeutics and the mechanisms leading to tumor-specific replication and antitumoral efficacy are now becoming apparent. The specific viruses in development include tumor-targeting herpes simplex viruses, autonomous parvoviruses, Newcastle disease viruses and adenovirus. Information is also available on antiviral immunology and viral defenses against host-mediated immunity. This approach has many potential attributes, in addition to potential hurdles that must be overcome.

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Year:  1996        PMID： 9015793     DOI： 10.1016/s1357-4310(97)81456-6

Source DB:  PubMed          Journal:  Mol Med Today        ISSN： 1357-4310


  21 in total

Review 1.  Replication-selective adenoviruses as oncolytic agents.

Authors:  C Heise; D H Kirn
Journal:  J Clin Invest       Date:  2000-04       Impact factor: 14.808

Review 2.  Gene delivery from replication-selective viruses: arming guided missiles in the war against cancer.

Authors:  T Hermiston
Journal:  J Clin Invest       Date:  2000-05       Impact factor: 14.808

Review 3.  The promise of gene therapy in gastrointestinal and liver diseases.

Authors:  J Prieto; M Herraiz; B Sangro; C Qian; G Mazzolini; I Melero; J Ruiz
Journal:  Gut       Date:  2003-05       Impact factor: 23.059

4.  Use of oncolytic viruses for the eradication of drug-resistant cancer cells.

Authors:  Dominik Wodarz
Journal:  J R Soc Interface       Date:  2009-02-06       Impact factor: 4.118

5.  Interferon γ improves the vaccination potential of oncolytic parvovirus H-1PV for the treatment of peritoneal carcinomatosis in pancreatic cancer.

Authors:  Svitlana P Grekova; Marc Aprahamian; Laurent Daeffler; Barbara Leuchs; Assia Angelova; Thomas Giese; Angel Galabov; Anette Heller; Nathalia A Giese; Jean Rommelaere; Zahari Raykov
Journal:  Cancer Biol Ther       Date:  2011-11-15       Impact factor: 4.742

6.  ODE models for oncolytic virus dynamics.

Authors:  Natalia L Komarova; Dominik Wodarz
Journal:  J Theor Biol       Date:  2010-01-18       Impact factor: 2.691

7.  Developing novel oncolytic adenoviruses through bioselection.

Authors:  Wen Yan; Galila Kitzes; Farid Dormishian; Lynda Hawkins; Adam Sampson-Johannes; Josh Watanabe; Jenny Holt; Vivian Lee; Thomas Dubensky; Ali Fattaey; Terry Hermiston; Allan Balmain; Yuqiao Shen
Journal:  J Virol       Date:  2003-02       Impact factor: 5.103

8.  Mathematical modeling of tumor therapy with oncolytic viruses: regimes with complete tumor elimination within the framework of deterministic models.

Authors:  Artem S Novozhilov; Faina S Berezovskaya; Eugene V Koonin; Georgy P Karev
Journal:  Biol Direct       Date:  2006-02-17       Impact factor: 4.540

9.  Towards predictive computational models of oncolytic virus therapy: basis for experimental validation and model selection.

Authors:  Dominik Wodarz; Natalia Komarova
Journal:  PLoS One       Date:  2009-01-30       Impact factor: 3.240

10.  Potent anti-tumor effects of a dual specific oncolytic adenovirus expressing apoptin in vitro and in vivo.

Authors:  Xiao Li; Yan Liu; Zhongmei Wen; Chang Li; Huijun Lu; Mingyao Tian; Kuoshi Jin; Lili Sun; Pegn Gao; Encheng Yang; Xiaohong Xu; Shifu Kan; Zhuoyue Wang; Yuhang Wang; Ningyi Jin
Journal:  Mol Cancer       Date:  2010-01-20       Impact factor: 27.401
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