| Literature DB >> 9011757 |
Abstract
The effects of olfactory bulbectomy (OBX) on galanin (GAL) gene expression in the locus coeruleus (LC) were examined with quantitative in situ hybridization histochemistry. OBX increased prepro-GAL levels 3 and 14 days after surgery, as compared to sham-operated controls. Levels of mRNA encoding prepro-neuropeptide Y (NPY) were unchanged, and levels of mRNA encoding tyrosine hydroxylase (TH) were elevated in the LC only on day 3. The results indicate that GAL gene expression in the LC increases after lesioning a terminal field.Entities:
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Year: 1996 PMID： 9011757 DOI： 10.1016/0169-328x(95)00295-4
Source DB: PubMed Journal: Brain Res Mol Brain Res ISSN： 0169-328X