Literature DB >> 9004915

Biological studies of analogues of glucose iodinated in positions 1, 2, or 3.

F Koumanov1, C Henry, C Ghezzi, G Bignan, C Morin, J P Mathieu, S Hamant, M Vidal, J de Leiris, M Comet.   

Abstract

Analogues of glucose labeled with 123 iodine in positions 1, 2 or 3 have been synthesized. The aim of this study was to examine their biological behavior in four experimental models in order to assess whether they could be used to evaluate the uptake of glucose with single photon emission computed tomography (SPECT). The results obtained have shown that none of these molecules enters the cell using the glucose transporter. Therefore, they cannot be used as tracers of glucose uptake.

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Year:  1996        PMID: 9004915     DOI: 10.1016/0969-8051(95)02004-7

Source DB:  PubMed          Journal:  Nucl Med Biol        ISSN: 0969-8051            Impact factor:   2.408


  1 in total

1.  First Quantitative Imaging of Organic Fluorine within Angiogenic Tissues by Particle Induced Gamma-Ray Emission (PIGE) Analysis: First PIGE Organic Fluorine Imaging.

Authors:  Sébastien Lavielle; Karine Gionnet; Richard Ortega; Guillaume Devès; Victor Kilarski; Katia Wehbe; Andreas Bikfalvi; Gérard Déléris
Journal:  Pharmaceutics       Date:  2011-03-09       Impact factor: 6.321

  1 in total

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