Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Phorbol ester-sensitive phospholipase D is mainly localized in the endoplasmic reticulum of BHK cells.

Literature DB >> 9003376

Phorbol ester-sensitive phospholipase D is mainly localized in the endoplasmic reticulum of BHK cells.

C Decker¹, M J Miro Obradors, D J Sillence, D Allan.

Abstract

The localization of phorbol ester-sensitive phospholipase D (PLD) in baby hamster kidney cells has been investigated by determining the subcellular distribution of the phosphatidylbutanol produced when the cells are incubated with phorbol 12-myristate 13-acetate and n-butanol. Results derived by isolation of plasma membrane vesicles from intact cells or by subcellular fractionation on a sucrose density gradient suggest the PLD is specific for phosphatidylcholine and its primary site of action is not the plasma membrane but the endoplasmic reticulum.

Entities: Chemical Species

Mesh：

Substances：

Year: 1996 PMID： 9003376 PMCID： PMC1218011 DOI： 10.1042/bj3200885

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

27 in total

1. A phospholipase D-mediated pathway for generating diacylglycerol in nuclei from Madin-Darby canine kidney cells.

Authors: M A Balboa; J Balsinde; E A Dennis; P A Insel
Journal: J Biol Chem Date: 1995-05-19 Impact factor: 5.157

Review 2. Signal transduction through lipid second messengers.

Authors: S Spiegel; D Foster; R Kolesnick
Journal: Curr Opin Cell Biol Date: 1996-04 Impact factor: 8.382

3. Plasma membrane vesicles from BHK and HL60 cells treated with merocyanine 540 and iodoacetamide.

Authors: J Whatmore; P Quinn; D Allan
Journal: Biochim Biophys Acta Date: 1993-11-07

4. Phosphatidic acid mobilized by phospholipase D is involved in the phorbol 12-myristate 13-acetate-induced G2 delay of A431 cells.

Authors: M Kaszkin; J Richards; V Kinzel
Journal: Biochem J Date: 1996-02-15 Impact factor: 3.857

5. Phospholipase D: a downstream effector of ARF in granulocytes.

Authors: S Cockcroft; G M Thomas; A Fensome; B Geny; E Cunningham; I Gout; I Hiles; N F Totty; O Truong; J J Hsuan
Journal: Science Date: 1994-01-28 Impact factor: 47.728

6. Phospholipid asymmetry in plasma membrane vesicles derived from BHK cells.

Authors: J L Whatmore; D Allan
Journal: Biochim Biophys Acta Date: 1994-06-01

7. Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.

Authors: N T Ktistakis; H A Brown; P C Sternweis; M G Roth
Journal: Proc Natl Acad Sci U S A Date: 1995-05-23 Impact factor: 11.205

8. Effects of brefeldin A on sphingomyelin transport and lipid synthesis in BHK21 cells.

Authors: K J Kallen; P Quinn; D Allan
Journal: Biochem J Date: 1993-01-01 Impact factor: 3.857

9. Accumulation of phosphatidylalcohol in cultured cells: use of subcellular fractionation to investigate phospholipase D activity during signal transduction.

Authors: Y S Edwards; A W Murray
Journal: Biochem J Date: 1995-06-01 Impact factor: 3.857

10. Concentration of intracellular hepatic apolipoprotein E in Golgi apparatus saccular distensions and endosomes.

Authors: S Dahan; J P Ahluwalia; L Wong; B I Posner; J J Bergeron
Journal: J Cell Biol Date: 1994-12 Impact factor: 10.539

5 in total

1. Involvement of PL-D in the alternate signal tranduction pathway of macrophages induced by an external stimulus.

Authors: R Bandyopadhyay; M K Basu
Journal: Mol Cell Biochem Date: 2000-01 Impact factor: 3.396

2. Intracellular cleavage of glycosylphosphatidylinositol by phospholipase D induces activation of protein kinase Calpha.

Authors: H Tsujioka; N Takami; Y Misumi; Y Ikehara
Journal: Biochem J Date: 1999-09-01 Impact factor: 3.857