Literature DB >> 9002045

Mapping of 10 novel microsatellites in the MHC class III region: application to the study of autoimmune disease.

S L Hsieh1, R E March, A Khanna, S J Cross, R D Campbell.   

Abstract

The MHC class III region contains many genes that are good candidates for involvement in autoimmune disease. We report the mapping and characterization of 10 novel (CA)n microsatellites spanning the region, which are highly informative and suitable for linkage and association studies. We used these markers to identify haplotypes of MHC class III microsatellite alleles in DNA from cell lines homozygous for MHC class II and class I alleles.

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Year:  1997        PMID： 9002045

Source DB:  PubMed          Journal:  J Rheumatol        ISSN： 0315-162X            Impact factor:   4.666


  3 in total

1.  Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci.

Authors:  S H Laval; A Timms; S Edwards; L Bradbury; S Brophy; A Milicic; L Rubin; K A Siminovitch; D E Weeks; A Calin; B P Wordsworth; M A Brown
Journal:  Am J Hum Genet       Date:  2001-02-27       Impact factor: 11.025

2.  Mutation screening in British 21-hydroxylase deficiency families and development of novel microsatellite based approaches to prenatal diagnosis.

Authors:  M Lako; S Ramsden; R D Campbell; T Strachan
Journal:  J Med Genet       Date:  1999-02       Impact factor: 6.318

3.  Evaluation of IgA deficiency in Sardinians indicates a susceptibility gene is encoded within the HLA class III region.

Authors:  F Cucca; Z B Zhu; A Khanna; F Cossu; M Congia; M Badiali; R Lampis; F Frau; S De Virgiliis; A Cao; M Arnone; P Piras; R D Campbell; M D Cooper; J E Volanakis; S H Powis
Journal:  Clin Exp Immunol       Date:  1998-01       Impact factor: 4.330
  3 in total

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