Literature DB >> 9001446

CYP2E1 genotypes and serum LAP in Japanese alcoholics.

R Miyatake1, H Suwaki, K Nakamura, Y Matsuo, K Iwahashi.   

Abstract

The genotypes of the ALDH2 and CYP2E1 loci of Japanese alcoholic patients were determined to investigate the susceptibility to alcoholic liver injury. In alcoholics with a liver-function disorder, a significant association was observed between the genotypes of the CYP2E1 loci and the serum level of a liver-derived enzyme, LAP. However, there was no significant association between the ALDH2 genotypes and liver dysfunction.

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Year:  1995        PMID: 9001446     DOI: 10.1016/0024-3205(95)00049-c

Source DB:  PubMed          Journal:  Life Sci        ISSN: 0024-3205            Impact factor:   5.037


  1 in total

1.  Strong protective effect of the aldehyde dehydrogenase gene (ALDH2) 504lys (*2) allele against alcoholism and alcohol-induced medical diseases in Asians.

Authors:  Dawei Li; Hongyu Zhao; Joel Gelernter
Journal:  Hum Genet       Date:  2011-11-20       Impact factor: 4.132

  1 in total

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