Interaction of nutrition and infection: plans for future research.

Future research concerning the interactions between infectious disease and nutritional status must extend our available knowledge concerning these two major problem areas. Critical studies must be designed in animal models as well as in man. The effects of malnutrition on immune responsiveness must be studied. Key information is lacking with respect to the utilization of host energy and protein during infection. Alterations in body chemistry are especially important in protracted diarrheal and respiratory diseases of children. A concensus has not yet been reached concerning the optimal approach to iron nutritional needs during infection or to those of other trace nutrients including the vitamins. Research needs in each of these areas are listed.