Literature DB >> 8999336

[Polymer-supported synthesis of biopolymers--foundations and applications].

K E Geckeler1, R Wacker.   

Abstract

The application of polymer supports for the synthesis of polypeptides, oligonucleotides, and oligosaccharides is presented in this article and discussed in view of their methodology. The fundamentals of the polymer-supported synthesis are described as well as the role of the polymer supports in the synthetic cycle, and the problems associated are debated. It is focused on typical polymer supports for each substance class, and an overview is given on recent tendencies of development in the polymer-supported methods of synthesis.

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Year:  1996        PMID： 8999336

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN： 0028-1042


  11 in total

1.  Automatic monitoring of solid phase synthesis of a decapeptide.

Authors:  K Brunfeldt; T Christensen; P Villemoes
Journal:  FEBS Lett       Date:  1972-05-01       Impact factor: 4.124

2.  Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method.

Authors:  R S Hodges; R B Merrifield
Journal:  Anal Biochem       Date:  1975-05-12       Impact factor: 3.365

3.  [A new technic for peptide synthesis: the alternating solid-liquid method].

Authors:  H Frank; H Hagenmaier
Journal:  Experientia       Date:  1975-01-15

4.  Studies on polynucleotides. LXXII. Deoxyribooligonucleotide synthesis on a polymer support.

Authors:  H Hayatsu; H G Khorana
Journal:  J Am Chem Soc       Date:  1967-07-19       Impact factor: 15.419

5.  Failure sequences in the solid phase synthesis of polypeptides.

Authors:  E Bayer; H Eckstein; K Hägele; W A König; W Brüning; H Hagenmaier; W Parr
Journal:  J Am Chem Soc       Date:  1970-03-25       Impact factor: 15.419

6.  [Polyreactions--mechanisms, taxonomy, relevance].

Authors:  K E Geckeler; J Stirn
Journal:  Naturwissenschaften       Date:  1993-11

7.  The synthesis of bovine insulin by the solid phase method.

Authors:  A Marglin; R B Merrifield
Journal:  J Am Chem Soc       Date:  1966-11-05       Impact factor: 15.419

8.  Synthesis of oligosaccharides on polymer supports. I. 6-O-(p-vinylbenzoyl) derivatives of glucopyranose and their copolymers with styrene.

Authors:  R D Guthrie; A D Jenkins; J Stehlícek
Journal:  J Chem Soc Perkin 1       Date:  1971

9.  Oligosaccharide synthesis on a light-sensitive solid support. I. The polymer and synthesis of isomaltose (6-O-alpha-D-glucopyranosyl-D-glucose).

Authors:  U Zehavi; A Patchornik
Journal:  J Am Chem Soc       Date:  1973-08-22       Impact factor: 15.419

10.  Chemoenzymic preparation of a glycoconjugate polymer having a sialyloligosaccharide: Neu5Ac alpha (2-->3)Gal beta (1-->4)GlcNAc.

Authors:  S Nishimura; K B Lee; K Matsuoka; Y C Lee
Journal:  Biochem Biophys Res Commun       Date:  1994-02-28       Impact factor: 3.575
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