Literature DB >> 89970

An alkaline protease in the delayed hypersensitivity skin lesions in the guinea-pigs.

T Kambara, M Hashimoto.   

Abstract

An alkaline hemoglobinolytic protease was extracted from the delayed hypersensitivity skin lesions induced by bovine gamma-globulin as an antigen in the guinea-pig. The enzyme was heat-labile and inhibited by thiol-blocking reagents. The mol.wt. was more than 100,000 and optimal pH around 9.

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Year:  1979        PMID： 89970     DOI： 10.1007/BF01949973

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  13 in total

1.  alpha-N-benzoylarginine-2-naphthylamide hydrolase (cathepsin B1 ?) from rat skin. II. Purification of the enzyme and demonstration of two inhibitors in the skin.

Authors:  M Järvinen; V K Hopsu-Havu
Journal:  Acta Chem Scand B       Date:  1975

2.  Alpha-N-benzoylarginine-2-naphthylamide hydrolase (cathepsin B1?) from rat skin. I. Preliminary experiments with skin extract.

Authors:  M Järvinen; V K Hopsu-Havu
Journal:  Acta Chem Scand B       Date:  1975

3.  Neutral proteases in the guinea-pig lymphocytes.

Authors:  T Kambara; M Hirata; T Hiraoka
Journal:  Experientia       Date:  1978-04-15

4.  Experimental study on the mechanisms of delayed hypersensitivity reaction, with special reference to emigration and function of mononuclear cells.

Authors:  T Kambara; H Katsuya; S Maeda
Journal:  Acta Pathol Jpn       Date:  1972-08

Review 5.  The biological activities of soluble lymphocyte products.

Authors:  E Pick; J L Turk
Journal:  Clin Exp Immunol       Date:  1972-01       Impact factor: 4.330

6.  Proteases associated with arthus skin lesions: their purification and biological significance (preliminary report).

Authors:  M Kono; M Muto; H Hayashi
Journal:  Tohoku J Exp Med       Date:  1968-03       Impact factor: 1.848

7.  Proteolytic enzymes in the skin. II. A comparative study of skin homogenates of five mammalian species.

Authors:  C T Jansén; V K Hopsu-Havu
Journal:  Acta Derm Venereol       Date:  1969       Impact factor: 4.437

8.  Microassay for cathepsin D shows an unexpected effedt of cycloheximide on limb-bone rudiments in organ culture.

Authors:  M B Hille; A J Barrett; J T Dingle; H B Fell
Journal:  Exp Cell Res       Date:  1970-08       Impact factor: 3.905

9.  The chemical mediation of delayed hypersensitivity skin reaction. II. Characterization of a macrophage-chemotactic factor from bovine gamma-globulin-induced skin reaction in guinea pigs.

Authors:  K Ueda; T Kambara
Journal:  Am J Pathol       Date:  1978-07       Impact factor: 4.307

10.  The chemical mediation of delayed hypersensitivity skin reactions. I. Purification of a macrophage-chemotactic factor from bovien gamma-globulin-induced skin reactions in guinea pigs.

Authors:  T Kambara; K Ueda; S Maeda
Journal:  Am J Pathol       Date:  1977-05       Impact factor: 4.307
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  1 in total

1.  A high-molecular-weight trypsinlike protease in the skin sites of delayed hypersensitivity in guinea pigs.

Authors:  T Nakamura; T Yamamoto; T Ishimatsu; T Kambara
Journal:  Am J Pathol       Date:  1984-02       Impact factor: 4.307
  1 in total

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