Literature DB >> 89969

Shape change of blood platelets induced by myelin basic protein.

A Laubscher, A Pletscher, C G Honegger, J G Richards, V Colombo.   

Abstract

Myelin basic protein (MBP) isolated from bovine spinal cord caused a marked shape change reaction of human blood platelets which was not accompanied by the release reaction and not inhibited by methysergide and spiroperidol. Only those basic proteins, including MBP, which had previously shown to exert neuronal depolarisation also induced the shape change reactions. Therefore, these findings may extend the use of platelets as neuronal models.

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Year:  1979        PMID: 89969     DOI: 10.1007/BF01949954

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  16 in total

1.  Effects of cationic polypeptides on thrombasthenic and afibrinogenemic blood platelets.

Authors:  J G White
Journal:  Am J Pathol       Date:  1972-09       Impact factor: 4.307

2.  Platelet surface charge and aggregation. Effects of polyelectrolytes.

Authors:  K A Gröttum
Journal:  Thromb Diath Haemorrh       Date:  1969-06-15

3.  Effect of the rapid shape change of platelets on the transmission and scattering of light through plasma.

Authors:  F Michal; G V Born
Journal:  Nat New Biol       Date:  1971-06-16

4.  Fixation of platelets for scanning and transmission electron microscopy.

Authors:  J C Mattson; P J Borgerding; D L Craft
Journal:  Stain Technol       Date:  1977-05

5.  Components in multiple sclerosis cerebrospinal fluid that are detected by radioimmunoassay for myelin basic protein.

Authors:  J H Carson; E Barbarese; P E Braun; T A McPherson
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

6.  Large scale preparation of myelin basic protein from central nervous tissue of several mammalian species.

Authors:  G E Deibler; R E Martenson; M W Kies
Journal:  Prep Biochem       Date:  1972

7.  Spinal fluid differences in experimental allergic encephalomyelitis and multiple sclerosis.

Authors:  H S Gutstein; S R Cohen
Journal:  Science       Date:  1978-01-20       Impact factor: 47.728

8.  Myelin basic protein depolarizes neuronal membranes.

Authors:  B H Gähwiler; C G Honegger
Journal:  Neurosci Lett       Date:  1979-03       Impact factor: 3.046

9.  Radioimmunoassay of myelin basic protein in spinal fluid. An index of active demyelination.

Authors:  S R Cohen; R M Herndon; G M McKhann
Journal:  N Engl J Med       Date:  1976-12-23       Impact factor: 91.245

10.  The effect of myelin basic protein (MBP) on the bioelectric activity of spinal cord and cerebellar neurones.

Authors:  C G Honegger; B H Gähwiler; H Isler
Journal:  Neurosci Lett       Date:  1977-05       Impact factor: 3.046

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  3 in total

1.  Shape change of blood platelets brought about by myelin basic protein and other basic polypeptides.

Authors:  A Laubscher; A Pletscher; C G Honegger; J G Richards
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-12       Impact factor: 3.000

2.  Myelin basic protein induces neuron-specific toxicity by directly damaging the neuronal plasma membrane.

Authors:  Jie Zhang; Xin Sun; Sixin Zheng; Xiao Liu; Jinghua Jin; Yi Ren; Jianhong Luo
Journal:  PLoS One       Date:  2014-09-25       Impact factor: 3.240

3.  Myelin basic protein charge isomers change macrophage polarization.

Authors:  Elene Tsitsilashvili; Maia Sepashvili; Marika Chikviladze; Lali Shanshiashvili; David Mikeladze
Journal:  J Inflamm Res       Date:  2019-01-23
  3 in total

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