Literature DB >> 8994965

Structural views of phosphoinositide-specific phospholipase C: signalling the way ahead.

R L Williams1, M Katan.   

Abstract

Recent structural studies of mammalian phosphoinositide-specific phospholipase C (PI-PLC) have begun to shed light on the mechanism whereby this family of effector enzymes is able to hydrolyze phospholipid substrates to yield second messengers. PI-PLC isozymes employ a variety of modules (PH domain, EF-hand domain, SH2 domain, SH3 domain and C2 domain) that are common in proteins involved in signal transduction to reversibly interact with membranes and protein components of the signalling pathways.

Entities:  

Mesh：

Substances：

Year:  1996        PMID： 8994965     DOI： 10.1016/s0969-2126(96)00146-3

Source DB:  PubMed          Journal:  Structure        ISSN： 0969-2126            Impact factor:   5.006


  17 in total

Review 1.  Structural features of heterotrimeric G-protein-coupled receptors and their modulatory proteins.

Authors:  H LeVine
Journal:  Mol Neurobiol       Date:  1999-04       Impact factor: 5.590

2.  Water deficit triggers phospholipase D activity in the resurrection plant Craterostigma plantagineum.

Authors:  W Frank; T Munnik; K Kerkmann; F Salamini; D Bartels
Journal:  Plant Cell       Date:  2000-01       Impact factor: 11.277

3.  The pleiotropic vegetative and sexual development phenotypes of Neurospora crassa arise from double mutants of the calcium signaling genes plc-1, splA2, and cpe-1.

Authors:  Ananya Barman; Ranjan Tamuli
Journal:  Curr Genet       Date:  2017-03-06       Impact factor: 3.886

4.  The SH3 domain, but not the catalytic domain, is required for phospholipase C-gamma1 to mediate epidermal growth factor-induced mitogenesis.

Authors:  Zhongjian Xie; Ying Chen; Sally D Pennypacker; Zhiguang Zhou; Dan Peng
Journal:  Biochem Biophys Res Commun       Date:  2010-07-16       Impact factor: 3.575

5.  Differential distribution of phospholipase C beta isoforms and diaglycerol kinase-beta in rodents cerebella corroborates the division of unipolar brush cells into two major subtypes.

Authors:  Gabriella Sekerková; Masahiko Watanabe; Marco Martina; Enrico Mugnaini
Journal:  Brain Struct Funct       Date:  2013-03-16       Impact factor: 3.270

6.  Selective interaction of the C2 domains of phospholipase C-beta1 and -beta2 with activated Galphaq subunits: an alternative function for C2-signaling modules.

Authors:  T Wang; S Pentyala; J T Elliott; L Dowal; E Gupta; M J Rebecchi; S Scarlata
Journal:  Proc Natl Acad Sci U S A       Date:  1999-07-06       Impact factor: 11.205

7.  Fluorescent phosphatidylinositol 4,5-bisphosphate derivatives with modified 6-hydroxy group as novel substrates for phospholipase C.

Authors:  Xiaoyang Wang; Matthew Barrett; John Sondek; T Kendall Harden; Qisheng Zhang
Journal:  Biochemistry       Date:  2012-06-22       Impact factor: 3.162

Review 8.  Signal-dependent membrane targeting by pleckstrin homology (PH) domains.

Authors:  M A Lemmon; K M Ferguson
Journal:  Biochem J       Date:  2000-08-15       Impact factor: 3.857

9.  Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-S.

Authors:  Jie Hong; Jose Behar; Jack Wands; Murray Resnick; Li Juan Wang; Ronald A Delellis; David Lambeth; Weibiao Cao
Journal:  Cancer Res       Date:  2010-01-19       Impact factor: 12.701

10.  Cell Death Control by Matrix Metalloproteinases.

Authors:  Dirk Zimmermann; Juan A Gomez-Barrera; Christian Pasule; Ursula B Brack-Frick; Elke Sieferer; Tim M Nicholson; Jens Pfannstiel; Annick Stintzi; Andreas Schaller
Journal:  Plant Physiol       Date:  2016-05-02       Impact factor: 8.340
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.