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Literature DB >> 8994778

Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics.

Abstract

beta-Lactamases are the principal mechanism of bacterial resistance to beta-lactam antibiotics. In recent years the number and variety of new beta-lactamases detected has risen at an alarming rate, apparently in response to the clinical use of novel classes of beta-lactam antibiotics. This paper reviews the structure and evolution of beta-lactamases in an attempt to understand the pressures that have contributed to their emergence.

Entities: Chemical

Mesh：

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Year: 1997 PMID： 8994778 DOI： 10.1093/clinids/24.supplement_1.s19

Source DB: PubMed Journal: Clin Infect Dis ISSN： 1058-4838 Impact factor: 9.079

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Cited

156 in total

1. Biochemical-genetic analysis and distribution of FAR-1, a class A beta-lactamase from Nocardia farcinica.

Authors: F Laurent; L Poirel; T Naas; E B Chaibi; R Labia; P Boiron; P Nordmann
Journal: Antimicrob Agents Chemother Date: 1999-07 Impact factor: 5.191

2. Class C beta-lactamases operate at the diffusion limit for turnover of their preferred cephalosporin substrates.

Authors: A Bulychev; S Mobashery
Journal: Antimicrob Agents Chemother Date: 1999-07 Impact factor: 5.191

3. Ability of the VITEK 2 advanced expert system To identify beta-lactam phenotypes in isolates of Enterobacteriaceae and Pseudomonas aeruginosa.

Authors: C C Sanders; M Peyret; E S Moland; C Shubert; K S Thomson; J M Boeufgras; W E Sanders
Journal: J Clin Microbiol Date: 2000-02 Impact factor: 5.948

4. ampR gene mutations that greatly increase class C beta-lactamase activity in Enterobacter cloacae.

Authors: A Kuga; R Okamoto; M Inoue
Journal: Antimicrob Agents Chemother Date: 2000-03 Impact factor: 5.191

5. Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae.

Authors: L Poirel; I Le Thomas; T Naas; A Karim; P Nordmann
Journal: Antimicrob Agents Chemother Date: 2000-03 Impact factor: 5.191

Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics.

1. Biochemical-genetic analysis and distribution of FAR-1, a class A beta-lactamase from Nocardia farcinica.

2. Class C beta-lactamases operate at the diffusion limit for turnover of their preferred cephalosporin substrates.

3. Ability of the VITEK 2 advanced expert system To identify beta-lactam phenotypes in isolates of Enterobacteriaceae and Pseudomonas aeruginosa.

4. ampR gene mutations that greatly increase class C beta-lactamase activity in Enterobacter cloacae.

5. Biochemical sequence analyses of GES-1, a novel class A extended-spectrum beta-lactamase, and the class 1 integron In52 from Klebsiella pneumoniae.

6. Molecular characterization of the SHV-11 beta-lactamase of Shigella dysenteriae.

7. The Red Menace: Emerging Issues in Antimicrobial Resistance in Gram-Negative Bacilli.

8. Impact of Antibiotic Resistance on the Treatment of Gram-negative Sepsis.

9. Binding properties of a peptide derived from beta-lactamase inhibitory protein.

10. Cloning and biochemical characterization of a class A beta-lactamase from Prevotella intermedia.