Literature DB >> 8992316

Toxoplasma gondii expressed sequence tags: insight into tachyzoite gene expression.

K L Wan1, J M Blackwell, J W Ajioka.   

Abstract

Analysis of DNA sequences from the 5' end of 239 directionally cloned Toxoplasma gondii RH strain tachyzoite-derived cDNAs revealed significant similarity to several classes of genes/proteins including 24 ribosomal proteins, five metabolic enzymes, four cell-cycle regulators and 15 previously cloned T. gondii genes. The remaining sequences with no significant match include several which were recovered more than once. The variety and redundancy of expressed sequence tags (ESTs GenBank accession numbers T62239-T62475) in this sample suggest that the tachyzoite cDNA library reflects tachyzoite gene expression. A large scale EST effort should uncover many new genes and provide a wealth of information about genes involved with the growth and proliferation of tachyzoites.

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Year:  1996        PMID: 8992316     DOI: 10.1016/0166-6851(95)02524-3

Source DB:  PubMed          Journal:  Mol Biochem Parasitol        ISSN: 0166-6851            Impact factor:   1.759


  13 in total

1.  Gene discovery in the apicomplexa as revealed by EST sequencing and assembly of a comparative gene database.

Authors:  Li Li; Brian P Brunk; Jessica C Kissinger; Deana Pape; Keliang Tang; Robert H Cole; John Martin; Todd Wylie; Mike Dante; Steven J Fogarty; Daniel K Howe; Paul Liberator; Carmen Diaz; Jennifer Anderson; Michael White; Maria E Jerome; Emily A Johnson; Jay A Radke; Christian J Stoeckert; Robert H Waterston; Sandra W Clifton; David S Roos; L David Sibley
Journal:  Genome Res       Date:  2003-03       Impact factor: 9.043

2.  Expressed sequence tags (ESTs) analysis of Acanthamoeba healyi.

Authors:  H H Kong; M Y Hwang; H K Kim; D I Chung
Journal:  Korean J Parasitol       Date:  2001-06       Impact factor: 1.341

3.  Receptor for retrograde transport in the apicomplexan parasite Toxoplasma gondii.

Authors:  Stacy L Pfluger; Holly V Goodson; Jennifer M Moran; Christine J Ruggiero; Xin Ye; Krista M Emmons; Kristin M Hager
Journal:  Eukaryot Cell       Date:  2005-02

4.  Common inheritance of chromosome Ia associated with clonal expansion of Toxoplasma gondii.

Authors:  Asis Khan; Ulrike Böhme; Krystyna A Kelly; Ellen Adlem; Karen Brooks; Mark Simmonds; Karen Mungall; Michael A Quail; Claire Arrowsmith; Tracey Chillingworth; Carol Churcher; David Harris; Matthew Collins; Nigel Fosker; Audrey Fraser; Zahra Hance; Kay Jagels; Sharon Moule; Lee Murphy; Susan O'Neil; Marie-Adele Rajandream; David Saunders; Kathy Seeger; Sally Whitehead; Thomas Mayr; Xuenan Xuan; Junichi Watanabe; Yutaka Suzuki; Hiroyuki Wakaguri; Sumio Sugano; Chihiro Sugimoto; Ian Paulsen; Aaron J Mackey; David S Roos; Neil Hall; Matthew Berriman; Bart Barrell; L David Sibley; James W Ajioka
Journal:  Genome Res       Date:  2006-08-10       Impact factor: 9.043

5.  Genetic and biochemical analysis of development in Toxoplasma gondii.

Authors:  J C Boothroyd; M Black; S Bonnefoy; A Hehl; L J Knoll; I D Manger; E Ortega-Barria; S Tomavo
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1997-09-29       Impact factor: 6.237

6.  The surface of Toxoplasma tachyzoites is dominated by a family of glycosylphosphatidylinositol-anchored antigens related to SAG1.

Authors:  I D Manger; A B Hehl; J C Boothroyd
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

7.  Exploring the transcriptome of the malaria sporozoite stage.

Authors:  S H Kappe; M J Gardner; S M Brown; J Ross; K Matuschewski; J M Ribeiro; J H Adams; J Quackenbush; J Cho; D J Carucci; S L Hoffman; V Nussenzweig
Journal:  Proc Natl Acad Sci U S A       Date:  2001-08-07       Impact factor: 11.205

8.  Expressed sequenced tags and new genes from the cattle tick, Boophilus microplus.

Authors:  A L Crampton; C Miller; G D Baxter; S C Barker
Journal:  Exp Appl Acarol       Date:  1998-03       Impact factor: 2.132

9.  A transient forward-targeting element for microneme-regulated secretion in Toxoplasma gondii.

Authors:  Susannah D Brydges; Jill M Harper; Fabiola Parussini; Isabelle Coppens; Vern B Carruthers
Journal:  Biol Cell       Date:  2008-04       Impact factor: 4.458

10.  The Alveolate Perkinsus marinus: biological insights from EST gene discovery.

Authors:  Sandeep J Joseph; José A Fernández-Robledo; Malcolm J Gardner; Najib M El-Sayed; Chih-Horng Kuo; Eric J Schott; Haiming Wang; Jessica C Kissinger; Gerardo R Vasta
Journal:  BMC Genomics       Date:  2010-04-07       Impact factor: 3.969

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