Literature DB >> 8988679

The extent of neck disease after regional failure during observation of the N0 neck.

P E Andersen1, E Cambronero, A R Shaha, J P Shah.   

Abstract

BACKGROUND: The optimum management of the N0 neck remains controversial. When the neck is observed it is hoped that close follow-up will detect regional failure at an early stage. To test this hypothesis we examined patients undergoing therapeutic neck dissection for newly developed neck metastases during observation after treatment of the primary tumor.
METHODS: A retrospective chart review of 47 patients undergoing neck dissection for regional failure after surgical treatment of the primary tumor and observation of the neck from 1987 to 1992 was performed. The median time to failure in the neck was 13 months.
RESULTS: The clinical neck stage at the time of neck dissection was N1 in 37, N2A in 6, N2B in 1, and N3 in 3. However, pathologic staging revealed stages of N1 in 19, N2A in 5, N2B in 20, and N3 in 3. Extracapsular spread (ECS) was present in 23 patients (49%). Overall 36 patients (77%) had adverse pathologic findings (N greater than 1 or ECS).
CONCLUSIONS: These data indicate that when observation is used for the neck at risk for metastasis, patients tend to fail with high stage disease in the neck. This supports the philosophy of elective treatment of the neck but cannot show whether elective treatment will improve survival.

Entities:  

Mesh:

Year:  1996        PMID: 8988679     DOI: 10.1016/s0002-9610(96)00290-5

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  16 in total

Review 1.  Management of the clinically negative (N0) neck.

Authors:  Karen T Pitman; Robert Dean
Journal:  Curr Oncol Rep       Date:  2002-01       Impact factor: 5.075

2.  Is there a role for lymphoscintigraphy and sentinel node biopsy in the management of the regional lymphatics in mucosal squamous cell carcinoma of the head and neck?

Authors:  Nicholas Hyde; Elizabeth Prvulovich
Journal:  Eur J Nucl Med Mol Imaging       Date:  2002-03-27       Impact factor: 9.236

Review 3.  Surgical management of the N0 neck in early stage T1-2 oral cancer; a personal perspective of early and late impalpable disease.

Authors:  R A Ord
Journal:  Oral Maxillofac Surg       Date:  2012-05-13

4.  Guidelines for the Surgical Management of Laryngeal Cancer: Korean Society of Thyroid-Head and Neck Surgery.

Authors:  Soon-Hyun Ahn; Hyun Jun Hong; Soon Young Kwon; Kee Hwan Kwon; Jong-Lyel Roh; Junsun Ryu; Jun Hee Park; Seung-Kuk Baek; Guk Haeng Lee; Sei Young Lee; Jin Choon Lee; Man Ki Chung; Young Hoon Joo; Yong Bae Ji; Jeong Hun Hah; Minsu Kwon; Young Min Park; Chang Myeon Song; Sung-Chan Shin; Chang Hwan Ryu; Doh Young Lee; Young Chan Lee; Jae Won Chang; Ha Min Jeong; Jae-Keun Cho; Wonjae Cha; Byung Joon Chun; Ik Joon Choi; Hyo Geun Choi; Kang Dae Lee
Journal:  Clin Exp Otorhinolaryngol       Date:  2017-01-03       Impact factor: 3.372

Review 5.  Sentinel lymph node biopsy for oral cancer: supporting evidence and recent novel developments.

Authors:  Marcus M Monroe; Stephen Y Lai
Journal:  Curr Oncol Rep       Date:  2014-05       Impact factor: 5.075

6.  Elective Neck Dissection in patients with stage T1-T2N0 carcinoma of the anterior tongue.

Authors:  D Mirea; R Grigore; D Safta; L Mirea; Cr Popescu; B Popescu; Svg Berteşteanu
Journal:  Hippokratia       Date:  2014-04       Impact factor: 0.471

7.  Prevalence and localization of nodal metastases in squamous cell carcinoma of the oral cavity: role and extension of neck dissection.

Authors:  Luca Oscar Redaelli De Zinis; Andrea Bolzoni; Cesare Piazza; Piero Nicolai
Journal:  Eur Arch Otorhinolaryngol       Date:  2006-09-27       Impact factor: 2.503

8.  Occult metastases from T1-T2 supraglottic carcinoma: role of primary tumor localization.

Authors:  Imdat Yüce; Sedat Cağli; Ali Bayram; Ercihan Güney
Journal:  Eur Arch Otorhinolaryngol       Date:  2008-11-05       Impact factor: 2.503

9.  Neck dissection for oral squamous cell carcinoma: our experience and a review of the literature.

Authors:  Pooja Rani; Yogesh Bhardwaj; Praveen Kumar Dass; Manoj Gupta; Divye Malhotra; Narottam Kumar Ghezta
Journal:  J Korean Assoc Oral Maxillofac Surg       Date:  2015-12-17

Review 10.  Current philosophy in the surgical management of neck metastases for head and neck squamous cell carcinoma.

Authors:  H Hakan Coskun; Jesus E Medina; K Thomas Robbins; Carl E Silver; Primož Strojan; Afshin Teymoortash; Phillip K Pellitteri; Juan P Rodrigo; Sandro J Stoeckli; Ashok R Shaha; Carlos Suárez; Dana M Hartl; Remco de Bree; Robert P Takes; Marc Hamoir; Karen T Pitman; Alessandra Rinaldo; Alfio Ferlito
Journal:  Head Neck       Date:  2014-06-30       Impact factor: 3.147

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